Helicobacter pylori Hp A-6

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp A-6 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and solitary cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical conditions found within the gastrointestinal tract of its mammalian hosts. As a host-associated microbe, H. pylori Hp A-6 occupies a niche that is specifically adapted to the gastric environment, utilizing its unique morphology and metabolic capabilities to survive in low-oxygen conditions. The microaerophilic nature of H. pylori Hp A-6 indicates that it requires a limited amount of oxygen for growth, reflecting its adaptation to the oxygen-poor regions of the stomach lining where it resides. This adaptation is crucial for its survival and potential interactions with the host's immune system and microbiota. Understanding the environmental preferences of H. pylori Hp A-6 not only provides insights into its physiological characteristics but also highlights the intricate relationships that exist between host-associated microbes and their environments. The ability of H. pylori to colonize the gastric epithelium suggests a complex evolutionary interplay, potentially influencing gastric health and disease dynamics in the host organism.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp A-6

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp A-6
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp A-6


Gene Summary

Adenine Count

499872 bp

Thymine Count

505077 bp

Guanine Count

321215 bp

Cytosine Count

327214 bp

Genome Length

1653378 bp

Protein-coding Genes

1652 genes

Non-Coding Genes

44 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
transcriptional regulatory family proteinHPHPA6_0001O25918+1 - 1114134.11
translation elongation factor tsHPHPA6_0002Q9ZJ71-290 - 135739732.1
ribosomal protein s2HPHPA6_0003B6JP48-1357 - 215130651.4
atp-dependent dna helicaseHPHPA6_0004Q03D71+2403 - 5279110543.0
na+/h+ antiporter nhaaHPHPA6_0005O26076+5303 - 661947730.9
preprotein translocase, yajc subunitHPHPA6_0006Q9ZJ67+6667 - 696011097.6
protein translocase subunit secdHPHPA6_0007Q9ZJ66+6961 - 853856686.1
protein-export membrane proteinHPHPA6_0008Q9ZJ65+8547 - 951836193.1
hypothetical proteinHPHPA6_0009Not Available+9528 - 986612230.5
leucine--trna ligaseHPHPA6_0010Q9ZJ63+9877 - 1229792915.8

Displaying genes 1 – 10 of 1696 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 93 metabolites