Helicobacter pylori Hp A-20

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp A-20 is a Gram-negative bacterium characterized by its spirilla shape and occurrence as single cells. This microbe thrives optimally at a temperature of 37.0°C, which aligns with the typical body temperature of its human hosts. H. pylori Hp A-20 is microaerophilic, indicating that it requires a reduced level of oxygen for growth, which is consistent with its ecological niche in the gastric environment, where oxygen levels are lower than in the atmosphere. As a host-associated organism, H. pylori Hp A-20 is commonly found in the stomachs of humans, where it may establish a complex relationship with its host. The microbe's unique adaptation to the acidic gastric environment may allow it to play a role in the local microbiome, potentially influencing gastric physiology and immune responses. Understanding the specific traits of H. pylori Hp A-20 is essential for further research into its ecological interactions and potential implications for human health. The adaptation of this strain to a microaerophilic habitat highlights the intricate balance between microbial life and host conditions, revealing the importance of environmental oxygen levels in shaping microbial communities within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp A-20

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp A-20
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp A-20


Gene Summary

Adenine Count

505906 bp

Thymine Count

512134 bp

Guanine Count

326444 bp

Cytosine Count

330116 bp

Genome Length

1674600 bp

Protein-coding Genes

1671 genes

Non-Coding Genes

77 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+262578 - 262592Not Available
Putative transcriptional regulator proteinHPHPA20_0288Not Available-268955 - 26977631102.5
Hypothetical proteinHPHPA20_0289I7H0I4-269782 - 27064532550.5
Hypothetical proteinHPHPA20_0290Not Available-270662 - 27154333808.9
Hypothetical proteinHPHPA20_0291Not Available-271599 - 27191912338.4
Putative dna repair proteinHPHPA20_0292Not Available-271923 - 27249221422.3
Hypothetical proteinHPHPA20_0293Not Available-272492 - 27325628243.6
Hypothetical proteinHPHPA20_0294Not Available-273293 - 27383820892.0
Hypothetical proteinHPHPA20_0295Not Available-273886 - 2741048339.37
Hypothetical proteinHPHPA20_0296Not Available-274106 - 27510137680.7

Displaying genes 1 – 10 of 1748 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 94 metabolites