Helicobacter pylori CPY3281

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori CPY3281 is a Gram-negative, microaerophilic bacterium characterized by its spiral shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, aligning with the typical temperature of the human gastric environment, which suggests a specialized adaptation to its host-associated habitat. The microaerophilic nature of H. pylori CPY3281 indicates that it requires reduced oxygen levels for growth, which is consistent with its colonization of the gastric mucosa, where oxygen concentration is lower than in the atmosphere. This adaptation not only supports its survival in the stomach but also contributes to its ability to persist in a challenging ecological niche dominated by acidic conditions. The unique morphological and physiological traits of H. pylori CPY3281 highlight its potential for intricate interactions with the host's immune system and gastric physiology. Understanding these characteristics can provide insights into the ecological dynamics of this bacterium within the human microbiome, particularly in relation to its role in gastrointestinal health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainCPY3281

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori CPY3281
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori CPY3281


Gene Summary

Adenine Count

491522 bp

Thymine Count

492723 bp

Guanine Count

311091 bp

Cytosine Count

311192 bp

Genome Length

1606528 bp

Protein-coding Genes

1708 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
23s ribosomal rnaNot AvailableNot Available+4477 - 7368Not Available
5s ribosomal rnaNot AvailableNot Available+7602 - 7717Not Available
pyruvate kinaseHPCPY3281_0013Not Available+7981 - 839715878.2
hypothetical proteinHPCPY3281_0014Not Available+8457 - 85885163.7
putative membrane proteinHPCPY3281_0015Not Available+9075 - 937712543.9
yihy family proteinHPCPY3281_0016Q15NT4-9432 - 1031034638.9
biotin synthaseHPCPY3281_0017Q1CRM5-10310 - 1115831477.8
hypothetical proteinHPCPY3281_0018Not Available+11289 - 114084647.6
type iii restriction-modification enzymeHPCPY3281_0019P44105+11552 - 1389791646.9
methyltransferaseHPCPY3281_0020P71366+13891 - 1582875034.6

Displaying genes 11 – 20 of 1749 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

93 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 93 metabolites