Gardnerella vaginalis 315-A

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis 315-A is a Gram-positive, nonsporulating rod-shaped bacterium that thrives in anaerobic environments, with an optimal growth temperature of 37.0°C. As a chemoheterotroph, it derives its energy from organic compounds, which positions it as a significant microbe within host-associated habitats, particularly in the human microbiome. This strain of Gardnerella vaginalis is known to play a role in the complex microbial ecosystem of the vagina, contributing to the maintenance of its ecological balance. While some strains of Gardnerella vaginalis have been studied for their association with dysbiosis and bacterial vaginosis, the specific traits of strain 315-A suggest a specialized adaptation to its anaerobic niche. The ability of Gardnerella vaginalis 315-A to flourish in low-oxygen conditions highlights its potential role in anaerobic metabolic processes within the host. This characteristic underlines the importance of understanding microbial interactions in the vaginal microbiome, as the anaerobic conditions provide a unique environment for the survival and activity of such bacteria. Further investigation into the ecological functions and interactions of strain 315-A could unveil insights into its contributions to host health and microbial community dynamics.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
Strain315-A

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis 315-A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Gardnerella vaginalis 315-A


Gene Summary

Adenine Count

483940 bp

Thymine Count

485102 bp

Guanine Count

336268 bp

Cytosine Count

347965 bp

Genome Length

1653275 bp

Protein-coding Genes

1284 genes

Non-Coding Genes

55 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinHMPREF9435_0965Not Available-11559 - 1333465416.0
peptidyl-prolyl cis-trans isomerase, fkbp-typeHMPREF9435_0966Not Available+13613 - 1460835361.4
hypothetical proteinHMPREF9435_0967B3DTU8-14755 - 1554328620.1
putative proline-specific permease proyHMPREF9435_0968A2RI86-15586 - 1705854393.6
efflux abc transporter, permease proteinHMPREF9435_0969Not Available-17137 - 19911102388.0
abc transporter, atp-binding proteinHMPREF9435_0970Q3A558-19933 - 2063425130.2
hypothetical proteinHMPREF9435_0971Not Available-20714 - 2133422688.1
aspartate-semialdehyde dehydrogenaseHMPREF9435_0972Q53612-21386 - 2245337912.6
act domain proteinHMPREF9435_0973P41403-22531 - 2311219983.0
putative aspartate kinaseHMPREF9435_0974Not Available-23183 - 2394726827.2

Displaying genes 31 – 40 of 1339 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

75 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00007052-dehydro-3-deoxy-D-arabinonateC5H7O5Chemical structure of 2-dehydro-3-deoxy-D-arabinonateNot available
Average147.107Da
Monoisotopic147.0298969Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001327L-fuconateC6H11O6Chemical structure of L-fuconateNot available
Average179.149Da
Monoisotopic179.0561117Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001775(9Z)-octadecenoateC18H33O2Chemical structure of (9Z)-octadecenoateNot available
Average281.4534Da
Monoisotopic281.2480553Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 75 metabolites