Blautia obeum A2-162

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Blautia

Description

Blautia obeum A2-162 is a microbe that thrives in a temperature range of 37°C to 42°C, classified as thermophilic. It is a chemoheterotroph that derives its energy from the breakdown of organic compounds, specifically amino acids and sugars. This microbe produces energy through anaerobic respiration, utilizing alternate electron acceptors in the absence of oxygen. Gram-staining reveals that Blautia obeum A2-162 has a Gram-positive cell wall, indicating a thick peptidoglycan layer. The microbe's shape is irregular, with a long, curved, or branched cell morphology. It is found in all body sites, including the gut, skin, and respiratory tract, across all possible species. Oxygen preference is characterized as a facultative anaerobe, meaning that while it can survive in the presence of oxygen, it can also thrive in its absence. Further investigation reveals that Blautia obeum A2-162 is a crucial member of the human gut microbiome, playing a role in the breakdown of dietary polysaccharides and amino acids. It has been isolated from human faeces and shown to dominate in the gut of patients with irritable bowel syndrome (IBS). Notably, Blautia obeum A2-162 has been proposed as a potential probiotic, due to its ability to modulate the gut microbiome and alleviate symptoms of IBS. Its unique metabolic properties make it an attractive target for further research into the treatment of gastrointestinal disorders.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusBlautia
SpeciesBlautia obeum
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Blautia obeum A2-162
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Blautia obeum A2-162

Accession NumberNC_021022.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

3506 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+783027 - 783038Not Available
site-specific integraseCK5_RS18425Not Available+791066 - 79227344896.6
AttlNot AvailableNot Available+792533 - 792549Not Available
pbecr4 domain-containing proteinCK5_RS03845Not Available+792960 - 79326211396.4
Hybrid sensor histidine kinase - response regulatorCK5_RS03850Not Available-793375 - 79367411131.4
cd1871a family cxxc motif-containing proteinCK5_RS03855Not Available+793731 - 7938955647.31
4fe-4s binding proteinCK5_RS03860Not Available+793888 - 79485635525.2
tlpa family protein disulfide reductaseCK5_RS03865Not Available+794870 - 79583835051.3
Terminase large subunitCK5_RS03870Not Available+795844 - 79661729853.5
hypothetical proteinCK5_RS03875Not Available+796717 - 79704012288.7

Displaying genes 1 – 10 of 3574 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

267 records
Metabolite IDMetabolite nameStructureCAS number
BASm0006317hydrogenobyrinate a,c-diamideC45H62N6O12Chemical structure of hydrogenobyrinate a,c-diamideNot available
Average879.021Da
Monoisotopic878.4425715Da
BASm0006855(R)-lipoateC8H14O2S2Chemical structure of (R)-lipoate1200-22-2
Average206.326Da
Monoisotopic206.0435211Da
BASm0008099(2E)-4-hydroxy-3-methylbut-2-enyl diphosphateC5H9O8P2Chemical structure of (2E)-4-hydroxy-3-methylbut-2-enyl diphosphateNot available
Average259.0677Da
Monoisotopic258.9772653Da
BASm0009028CDP-alpha-D-glucoseC15H23N3O16P2Chemical structure of CDP-alpha-D-glucoseNot available
Average563.3011Da
Monoisotopic563.055354727Da
BASm0009937Adenosine diphosphate riboseC15H23N5O14P2Chemical structure of Adenosine diphosphate ribose20762-30-5
Average559.3157Da
Monoisotopic559.0716735Da
BASm0010887(4R,5S)-dethiobiotinC10H18N2O3Chemical structure of (4R,5S)-dethiobiotin533-48-2
Average214.2615Da
Monoisotopic214.1317425Da
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da
BASm0014031Butyric acidC4H8O2Chemical structure of Butyric acid107-92-6
Average88.1051Da
Monoisotopic88.0524295Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da

Displaying 41–50 of 267 metabolites