Blautia obeum A2-162

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Blautia

Description

Blautia obeum A2-162 is a microbe that thrives in a temperature range of 37°C to 42°C, classified as thermophilic. It is a chemoheterotroph that derives its energy from the breakdown of organic compounds, specifically amino acids and sugars. This microbe produces energy through anaerobic respiration, utilizing alternate electron acceptors in the absence of oxygen. Gram-staining reveals that Blautia obeum A2-162 has a Gram-positive cell wall, indicating a thick peptidoglycan layer. The microbe's shape is irregular, with a long, curved, or branched cell morphology. It is found in all body sites, including the gut, skin, and respiratory tract, across all possible species. Oxygen preference is characterized as a facultative anaerobe, meaning that while it can survive in the presence of oxygen, it can also thrive in its absence. Further investigation reveals that Blautia obeum A2-162 is a crucial member of the human gut microbiome, playing a role in the breakdown of dietary polysaccharides and amino acids. It has been isolated from human faeces and shown to dominate in the gut of patients with irritable bowel syndrome (IBS). Notably, Blautia obeum A2-162 has been proposed as a potential probiotic, due to its ability to modulate the gut microbiome and alleviate symptoms of IBS. Its unique metabolic properties make it an attractive target for further research into the treatment of gastrointestinal disorders.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusBlautia
SpeciesBlautia obeum
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Blautia obeum A2-162
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Blautia obeum A2-162

Accession NumberNC_021022.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

3506 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+783027 - 783038Not Available
site-specific integraseCK5_RS18425Not Available+791066 - 79227344896.6
AttlNot AvailableNot Available+792533 - 792549Not Available
pbecr4 domain-containing proteinCK5_RS03845Not Available+792960 - 79326211396.4
Hybrid sensor histidine kinase - response regulatorCK5_RS03850Not Available-793375 - 79367411131.4
cd1871a family cxxc motif-containing proteinCK5_RS03855Not Available+793731 - 7938955647.31
4fe-4s binding proteinCK5_RS03860Not Available+793888 - 79485635525.2
tlpa family protein disulfide reductaseCK5_RS03865Not Available+794870 - 79583835051.3
Terminase large subunitCK5_RS03870Not Available+795844 - 79661729853.5
hypothetical proteinCK5_RS03875Not Available+796717 - 79704012288.7

Displaying genes 1 – 10 of 3574 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

267 records
Metabolite IDMetabolite nameStructureCAS number
BASm00040072-methoxy-6-all-trans-octaprenyl-1,4-benzoquinolC47H72O3Chemical structure of 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinolNot available
Average685.0728Da
Monoisotopic684.5481462Da
BASm0004098L-alanyl-L-glutamateC8H13N2O5Chemical structure of L-alanyl-L-glutamateNot available
Average217.1992Da
Monoisotopic217.082446536Da
BASm0004157menaquinol-8C51H74O2Chemical structure of menaquinol-8Not available
Average719.1321Da
Monoisotopic718.568881612Da
BASm00041782-demethylmenaquinol-8C50H72O2Chemical structure of 2-demethylmenaquinol-8Not available
Average705.1055Da
Monoisotopic704.553231548Da
BASm0004183butane-1-sulfonateC4H9O3SChemical structure of butane-1-sulfonateNot available
Average137.177Da
Monoisotopic137.027239844Da
BASm0004344(2Z,6E,10E)-geranylgeranyl diphosphateC20H33O7P2Chemical structure of (2Z,6E,10E)-geranylgeranyl diphosphateNot available
Average447.426Da
Monoisotopic447.171798138Da
BASm0005442glycyl-L-asparagineC6H11N3O4Not availableNot available
Average189.171Da
Monoisotopic189.074955846Da
BASm0005445L-methionyl-L-alanineC8H16N2O3SChemical structure of L-methionyl-L-alanineNot available
Average220.29Da
Monoisotopic220.088163557Da
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm0006316hydrogenobyrinateC45H60N4O14Chemical structure of hydrogenobyrinateNot available
Average880.989Da
Monoisotopic880.4106026Da

Displaying 31–40 of 267 metabolites