Blautia obeum A2-162

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Blautia

Description

Blautia obeum A2-162 is a microbe that thrives in a temperature range of 37°C to 42°C, classified as thermophilic. It is a chemoheterotroph that derives its energy from the breakdown of organic compounds, specifically amino acids and sugars. This microbe produces energy through anaerobic respiration, utilizing alternate electron acceptors in the absence of oxygen. Gram-staining reveals that Blautia obeum A2-162 has a Gram-positive cell wall, indicating a thick peptidoglycan layer. The microbe's shape is irregular, with a long, curved, or branched cell morphology. It is found in all body sites, including the gut, skin, and respiratory tract, across all possible species. Oxygen preference is characterized as a facultative anaerobe, meaning that while it can survive in the presence of oxygen, it can also thrive in its absence. Further investigation reveals that Blautia obeum A2-162 is a crucial member of the human gut microbiome, playing a role in the breakdown of dietary polysaccharides and amino acids. It has been isolated from human faeces and shown to dominate in the gut of patients with irritable bowel syndrome (IBS). Notably, Blautia obeum A2-162 has been proposed as a potential probiotic, due to its ability to modulate the gut microbiome and alleviate symptoms of IBS. Its unique metabolic properties make it an attractive target for further research into the treatment of gastrointestinal disorders.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusBlautia
SpeciesBlautia obeum
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Blautia obeum A2-162
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Blautia obeum A2-162

Accession NumberNC_021022.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

3506 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+783027 - 783038Not Available
site-specific integraseCK5_RS18425Not Available+791066 - 79227344896.6
AttlNot AvailableNot Available+792533 - 792549Not Available
pbecr4 domain-containing proteinCK5_RS03845Not Available+792960 - 79326211396.4
Hybrid sensor histidine kinase - response regulatorCK5_RS03850Not Available-793375 - 79367411131.4
cd1871a family cxxc motif-containing proteinCK5_RS03855Not Available+793731 - 7938955647.31
4fe-4s binding proteinCK5_RS03860Not Available+793888 - 79485635525.2
tlpa family protein disulfide reductaseCK5_RS03865Not Available+794870 - 79583835051.3
Terminase large subunitCK5_RS03870Not Available+795844 - 79661729853.5
hypothetical proteinCK5_RS03875Not Available+796717 - 79704012288.7

Displaying genes 1 – 10 of 3574 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

267 records
Metabolite IDMetabolite nameStructureCAS number
BASm0003276S-(5-deoxy-D-ribos-5-yl)-L-homocysteineC9H17NO6SChemical structure of S-(5-deoxy-D-ribos-5-yl)-L-homocysteine15912-98-8
Average267.299Da
Monoisotopic267.077658Da
BASm0003296L-ribulose 5-phosphateC5H9O8PChemical structure of L-ribulose 5-phosphateNot available
Average228.094Da
Monoisotopic228.0046014Da
BASm00034334-amino-4-deoxychorismateC10H10NO5Chemical structure of 4-amino-4-deoxychorismate133442-18-9
Average224.193Da
Monoisotopic224.056446006Da
BASm0003566cob(I)yrinate a,c diamideC45H61CoN6O12Chemical structure of cob(I)yrinate a,c diamideNot available
Average936.932Da
Monoisotopic936.3679466Da
BASm0003568precorrin-8XC45H60N4O14Chemical structure of precorrin-8XNot available
Average880.989Da
Monoisotopic880.4106026Da
BASm00036917,8-dihydroneopterin 3'-phosphateC9H12N5O7PChemical structure of 7,8-dihydroneopterin 3'-phosphateNot available
Average333.1946Da
Monoisotopic333.047434275Da
BASm00036954-phospho-D-erythronateC4H6O8PChemical structure of 4-phospho-D-erythronateNot available
Average213.059Da
Monoisotopic212.9816749Da
BASm0003810propanoyl phosphateC3H5O5PChemical structure of propanoyl phosphate121-69-7
Average152.043Da
Monoisotopic151.9885574Da
BASm0003926sirohemeC42H36FeN4O16Not available52553-42-1
Average908.611Da
Monoisotopic908.151956Da
BASm0003987cob(I)alaminC62H88CoN13O14PChemical structure of cob(I)alamin18534-66-2
Average1329.3478Da
Monoisotopic1328.564331Da

Displaying 21–30 of 267 metabolites