Prevotella melaninogenica ATCC 25845

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Prevotellaceae

Genus

Prevotella

Description

Prevotella melaninogenica ATCC 25845 is a mesophilic, Gram-negative, rod-shaped bacterium that belongs to the family Prevotellaceae. As a chemoheterotroph, it derives its energy from the breakdown of organic compounds, utilizing a variety of carbon sources as its energy source. This bacterium is capable of producing energy through the process of fermentation, where it converts glucose and other sugars into lactate, ethanol, and carbon dioxide. P. melaninogenica ATCC 25845 is classified as a facultative anaerobe, meaning it can grow in both aerobic and anaerobic environments. It exhibits a growth preference for microaerobic conditions, where oxygen levels are moderate, making it thrive in areas with limited oxygen availability. Its cell shape is characterized by a rod-like morphology, with dimensions ranging from 0.5-1.5 μm in width and 2-5 μm in length. P. melaninogenica ATCC 25845 is commonly found in the oral cavity, respiratory tract, and gastrointestinal tract of humans, as well as in soil and sediments. The bacterium's metabolic capabilities are supplemented by its ability to produce melanin, a pigment produced through the oxidation of tyrosine. This unique characteristic allows it to thrive in environments with high levels of tyrosine, such as those found in soil and decaying matter. In addition to its vital functions in the ecosystem, P. melaninogenica ATCC 25845 has earned recognition for its potential role in human health. Research has indicated that this microbe is involved in the breakdown of complex lipids and the production of bioactive compounds, which may have therapeutic applications. Furthermore, studies have suggested that alterations in the gut microbiome, including changes in the presence of P. melaninogenica ATCC 25845, may be associated with various human diseases, such as inflammatory bowel disease and colon cancer.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyPrevotellaceae
GenusPrevotella
SpeciesPrevotella melaninogenica
StrainATCC 25845

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceNot Available
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Prevotella melaninogenica ATCC 25845

Accession NumberNC_014371.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1001 genes

Non-Coding Genes

16 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
oligosaccharide flippase family proteinHMPREF0659_RS04545Not Available-1139451 - 114097757136.1
duf6078 family proteinHMPREF0659_RS04550Not Available-1141333 - 114180018389.7
porin family proteinHMPREF0659_RS04555Not Available+1142593 - 114334227907.4
acyloxyacyl hydrolaseHMPREF0659_RS04560Not Available+1143359 - 114460347669.4
methionyl-trna formyltransferaseHMPREF0659_RS04565Not Available-1144874 - 114589638182.1
chloride channel proteinHMPREF0659_RS04570Not Available-1145954 - 114775066109.5
l-threonylcarbamoyladenylate synthaseHMPREF0659_RS04575Not Available-1147763 - 114833221008.2
rok family proteinHMPREF0659_RS04580Not Available-1148959 - 114996035252.4
lyse family translocatorHMPREF0659_RS04585Not Available+1150092 - 115077825083.8
duf4924 family proteinHMPREF0659_RS04590Not Available+1150788 - 115139623869.8

Displaying genes 1931 – 1940 of 2452 in total

Pathways

1 pathway

Metabolites

2 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014318Salicylic acidC7H6O3Chemical structure of Salicylic acidNULL
Average138.122Da
Monoisotopic138.031694053Da
BASm0034470Ethyl salicylateC9H10O3Chemical structure of Ethyl salicylateNULL
Average166.1739Da
Monoisotopic166.062994186Da

Displaying 1–2 of 2 metabolites