Prevotella melaninogenica ATCC 25845

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Prevotellaceae

Genus

Prevotella

Description

Prevotella melaninogenica ATCC 25845 is a mesophilic, Gram-negative, rod-shaped bacterium that belongs to the family Prevotellaceae. As a chemoheterotroph, it derives its energy from the breakdown of organic compounds, utilizing a variety of carbon sources as its energy source. This bacterium is capable of producing energy through the process of fermentation, where it converts glucose and other sugars into lactate, ethanol, and carbon dioxide. P. melaninogenica ATCC 25845 is classified as a facultative anaerobe, meaning it can grow in both aerobic and anaerobic environments. It exhibits a growth preference for microaerobic conditions, where oxygen levels are moderate, making it thrive in areas with limited oxygen availability. Its cell shape is characterized by a rod-like morphology, with dimensions ranging from 0.5-1.5 μm in width and 2-5 μm in length. P. melaninogenica ATCC 25845 is commonly found in the oral cavity, respiratory tract, and gastrointestinal tract of humans, as well as in soil and sediments. The bacterium's metabolic capabilities are supplemented by its ability to produce melanin, a pigment produced through the oxidation of tyrosine. This unique characteristic allows it to thrive in environments with high levels of tyrosine, such as those found in soil and decaying matter. In addition to its vital functions in the ecosystem, P. melaninogenica ATCC 25845 has earned recognition for its potential role in human health. Research has indicated that this microbe is involved in the breakdown of complex lipids and the production of bioactive compounds, which may have therapeutic applications. Furthermore, studies have suggested that alterations in the gut microbiome, including changes in the presence of P. melaninogenica ATCC 25845, may be associated with various human diseases, such as inflammatory bowel disease and colon cancer.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyPrevotellaceae
GenusPrevotella
SpeciesPrevotella melaninogenica
StrainATCC 25845

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceNot Available
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Prevotella melaninogenica ATCC 25845

Accession NumberNC_014371.1

Gene Summary

Adenine Count

406073 bp

Thymine Count

402426 bp

Guanine Count

281778 bp

Cytosine Count

281597 bp

Genome Length

1371874 bp

Protein-coding Genes

1001 genes

Non-Coding Genes

16 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
rod shape-determining protein mrecHMPREF0659_RS02125Not Available+547695 - 54857933026.5
rod shape-determining protein mredHMPREF0659_RS02130Not Available+548695 - 54919519042.7
penicillin-binding protein 2HMPREF0659_RS02135Not Available+549199 - 55156588872.8
rod shape-determining protein rodaHMPREF0659_RS02140Not Available+551555 - 55303055002.1
gliding motility lipoprotein gldhHMPREF0659_RS02145Not Available-553349 - 55384319134.3
stage 0 sporulation family proteinHMPREF0659_RS02150Not Available-553840 - 55519251250.8
atp-binding proteinHMPREF0659_RS02155Not Available-555357 - 55649643504.6
methylenetetrahydrofolate reductaseHMPREF0659_RS02160Not Available-556515 - 55751637812.2
glycoside hydrolase 5 family proteinHMPREF0659_RS02165Not Available+558566 - 55982847952.1
type i phosphomannose isomerase catalytic subunitHMPREF0659_RS02170Not Available+560185 - 56114736163.5

Displaying genes 1441 – 1450 of 2452 in total

Pathways

1 pathway

Metabolites

2 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014318Salicylic acidC7H6O3Chemical structure of Salicylic acidNULL
Average138.122Da
Monoisotopic138.031694053Da
BASm0034470Ethyl salicylateC9H10O3Chemical structure of Ethyl salicylateNULL
Average166.1739Da
Monoisotopic166.062994186Da

Displaying 1–2 of 2 metabolites