Bifidobacterium animalis subsp. lactis BB-12

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium animalis subsp. lactis BB-12 is a gram-positive, rod-shaped bacterium that thrives in mesophilic conditions, classified as a facultative anaerobe and a heterotroph, capable of metabolizing a variety of carbohydrates. This probiotic microorganism is predominantly found in the human gastrointestinal tract, particularly in the colon, as well as in the intestines of various animals, including livestock and pets. Its ability to adapt to environments rich in nutrients makes it a prominent member of the gut microbiota. The gram-positive nature of BB-12 indicates a thick peptidoglycan layer in its cell wall, a characteristic that contributes to its stability and resilience in acidic environments, such as the stomach. Its rod shape is typical of many bifidobacteria, allowing for efficient colonization and interaction with the gut lining. BB-12's preferring mesophilic conditions indicates it thrives optimally between 30-37°C, which aligns well with the human body temperature, facilitating its presence as a beneficial gut inhabitant. As a facultative anaerobe, BB-12 can grow in both the presence or absence of oxygen, which enables it to thrive in various niches within the gut. Its heterotrophic metabolism means it relies on organic compounds for energy, primarily fermenting carbohydrates to produce beneficial short-chain fatty acids, aiding in gut health and regulation of intestinal microbiota. Bifidobacterium animalis subsp. lactis BB-12 is particularly revered in the food and health industries for its probiotic properties, enhancing gut health, improving lactose digestion, and modulating the immune response. Research has shown that this strain can potentially reduce the risk of gastrointestinal disorders and contribute to overall well-being when included in functional foods and dietary supplements. Its ability to survive in processed dairy products further underscores its significance in functional nutrition and public health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium animalis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium animalis subsp. lactis BB-12
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature39
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium animalis subsp. lactis BB-12


Gene Summary

Adenine Count

383455 bp

Thymine Count

384690 bp

Guanine Count

587452 bp

Cytosine Count

588555 bp

Genome Length

1944152 bp

Protein-coding Genes

1556 genes

Non-Coding Genes

67 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
chromosomal replication initiator protein dnaaBIF_RS00005Not Available+1 - 175264805.0
dna polymerase iii subunit betaBIF_RS00010Not Available+2356 - 348040668.3
dna replication/repair protein recfBIF_RS00015Not Available+3526 - 495351830.4
dcia family proteinBIF_RS00020Not Available+4950 - 545318849.8
dna topoisomerase (atp-hydrolyzing) subunit bBIF_RS00025Not Available+5644 - 776178154.8
dna gyrase subunit aBIF_RS00030Not Available+7830 - 10592102097.0
duf3566 domain-containing proteinBIF_RS00035Not Available+10718 - 1125419102.4
vanz family proteinBIF_RS00040Not Available+11458 - 1253140800.6
paqr family membrane homeostasis protein trhaBIF_RS00045Not Available-12612 - 1340629726.5
nadp-specific glutamate dehydrogenaseBIF_RS00050Not Available-13885 - 1523149032.9

Displaying genes 1 – 10 of 1623 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites