Lactobacillus iners DSM 13335

Gram-positiveRodFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Lactobacillaceae

Genus

Lactobacillus

Description

Lactobacillus iners DSM 13335 is a Gram-positive, rod-shaped bacterium, categorized as a facultative anaerobe, which thrives optimally in a temperature range of 30–37°C. This microbe is a member of the Lactobacillus genus, known for its role in fermentative processes and is primarily classified as a heterotroph due to its requirement for organic compounds as a carbon source. Lactobacillus iners is predominantly found in various body sites, especially in the female genital microbiota, where it plays a crucial role in maintaining vaginal health. It is also present in the gastrointestinal tract and oral cavity, contributing to the microbial diversity and function within these ecosystems. The bacterium's ability to thrive in diverse environments and its adaptability are pivotal for its survival and ecological roles. As a facultative anaerobe, Lactobacillus iners can survive in both aerobic and anaerobic conditions, showcasing its versatility. In oxygen-rich environments, it can perform respiration, while in low-oxygen conditions, it switches to fermentation, allowing it to colonize various niches in the body effectively.Lactobacillus iners is particularly interesting due to its dynamic role in the vaginal microbiome. It is often associated with a state of health, helping to prevent infections by producing lactic acid, lowering the pH, and inhibiting the growth of pathogenic organisms. Its presence is linked to a reduced risk of conditions such as bacterial vaginosis, highlighting its importance in maintaining microbial balance and overall health in the female reproductive system. Its probiotic potential is also a topic of ongoing research, emphasizing its significance in therapeutic applications.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyLactobacillaceae
GenusLactobacillus
SpeciesLactobacillus iners
StrainDSM 13335

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Lactobacillus iners DSM 13335
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Lactobacillus iners DSM 13335


Gene Summary

Adenine Count

432121 bp

Thymine Count

424599 bp

Guanine Count

215519 bp

Cytosine Count

197245 bp

Genome Length

1269484 bp

Protein-coding Genes

1208 genes

Non-Coding Genes

46 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
5s ribosomal rnaNot AvailableNot Available+1 - 115Not Available
16s ribosomal rnaNot AvailableNot Available+105 - 1663Not Available
23s ribosomal rnaNot AvailableNot Available+178 - 3075Not Available
hypothetical proteinHMPREF0520_0002Not Available-659 - 134425462.6
lpxtg-motif cell wall anchor domain proteinHMPREF0520_0003Not Available+1388 - 16037771.33
hypothetical proteinHMPREF0520_0004Not Available+1742 - 19668427.08
hypothetical proteinHMPREF0520_0005Not Available+1970 - 266826775.6
hypothetical proteinHMPREF0520_0006Not Available+2714 - 405750396.3
hypoxanthine phosphoribosyltransferaseHMPREF0520_0007Not Available+4150 - 471621125.6
dead/deah box helicaseHMPREF0520_0008Not Available+4772 - 600746843.3

Displaying genes 11 – 20 of 1254 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

23 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014037Fumaric acidC4H4O4Chemical structure of Fumaric acid110-17-8
Average116.0722Da
Monoisotopic116.010958616Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014042Oxoglutaric acidC5H6O5Chemical structure of Oxoglutaric acid328-50-7
Average146.0981Da
Monoisotopic146.021523302Da
BASm0014044Orotic acidC5H4N2O4Chemical structure of Orotic acid65-86-1
Average156.0963Da
Monoisotopic156.017106626Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da

Displaying 1–10 of 23 metabolites