Lactobacillus iners DSM 13335

Gram-positiveRodFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Lactobacillaceae

Genus

Lactobacillus

Description

Lactobacillus iners DSM 13335 is a Gram-positive, rod-shaped bacterium, categorized as a facultative anaerobe, which thrives optimally in a temperature range of 30–37°C. This microbe is a member of the Lactobacillus genus, known for its role in fermentative processes and is primarily classified as a heterotroph due to its requirement for organic compounds as a carbon source. Lactobacillus iners is predominantly found in various body sites, especially in the female genital microbiota, where it plays a crucial role in maintaining vaginal health. It is also present in the gastrointestinal tract and oral cavity, contributing to the microbial diversity and function within these ecosystems. The bacterium's ability to thrive in diverse environments and its adaptability are pivotal for its survival and ecological roles. As a facultative anaerobe, Lactobacillus iners can survive in both aerobic and anaerobic conditions, showcasing its versatility. In oxygen-rich environments, it can perform respiration, while in low-oxygen conditions, it switches to fermentation, allowing it to colonize various niches in the body effectively.Lactobacillus iners is particularly interesting due to its dynamic role in the vaginal microbiome. It is often associated with a state of health, helping to prevent infections by producing lactic acid, lowering the pH, and inhibiting the growth of pathogenic organisms. Its presence is linked to a reduced risk of conditions such as bacterial vaginosis, highlighting its importance in maintaining microbial balance and overall health in the female reproductive system. Its probiotic potential is also a topic of ongoing research, emphasizing its significance in therapeutic applications.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyLactobacillaceae
GenusLactobacillus
SpeciesLactobacillus iners
StrainDSM 13335

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Lactobacillus iners DSM 13335
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Lactobacillus iners DSM 13335


Gene Summary

Adenine Count

432121 bp

Thymine Count

424599 bp

Guanine Count

215519 bp

Cytosine Count

197245 bp

Genome Length

1269484 bp

Protein-coding Genes

1208 genes

Non-Coding Genes

46 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
IntHMPREF0520_0631Not Available+660989 - 66150119157.9
AttlNot AvailableNot Available+661259 - 661284Not Available
Site-specific recombinaseHMPREF0520_0632Not Available+661562 - 66196014750.4
hypothetical proteinHMPREF0520_0633Not Available+661950 - 66259424914.7
Terminase large subunitHMPREF0520_0634Not Available+663250 - 66357311872.6
Hypothetical proteinHMPREF0520_0635Not Available+663712 - 66475540398.7
Portal proteinHMPREF0520_0636Not Available+664801 - 6649987421.89
Phage portal protein, hk97 familyHMPREF0520_0637Not Available+664982 - 66528411506.9
AttrNot AvailableNot Available+667054 - 667079Not Available
hypothetical proteinHMPREF0520_0001Not Available+1 - 65024564.7

Displaying genes 1 – 10 of 1254 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

77 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0003070D-methionineC5H11NO2SChemical structure of D-methionine348-67-4
Average149.211Da
Monoisotopic149.0510493Da
BASm0003462(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinateC13H19N4O12PChemical structure of (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate3031-95-6
Average454.2833Da
Monoisotopic454.0737086Da
BASm0012579N-acetyl-D-glutamateC7H9NO5Not availableNot available
Average187.152Da
Monoisotopic187.049169554Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014037Fumaric acidC4H4O4Chemical structure of Fumaric acid110-17-8
Average116.0722Da
Monoisotopic116.010958616Da

Displaying 1–10 of 77 metabolites