Actinomyces urogenitalis DSM 15434

Gram-positiveFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Actinomyces

Description

Actinomyces urogenitalis DSM 15434 is a gram-positive, rod-shaped bacterium that is classified as a facultative anaerobe, thriving at mesophilic temperatures ranging from 20°C to 45°C. As a chemoheterotroph, this microbe obtains its energy and carbon from organic compounds, which it metabolizes in various environments. A. urogenitalis is found predominantly in the urogenital tracts of humans, but it can also be isolated from other body sites, including the oral cavity, gastrointestinal tract, and respiratory system. The gram-positive nature of A. urogenitalis indicates a thick peptidoglycan layer in its cell wall, which contributes to its robustness and ability to survive in a variety of conditions. The rod shape allows for efficient mobility and colonization of host tissues. As a facultative anaerobe, A. urogenitalis can adapt to both aerobic and anaerobic environments, showcasing its flexibility in utilizing oxygen or fermentation pathways based on environmental availability. The classification as a chemoheterotroph signifies that A. urogenitalis relies on organic substrates for growth, making it an integral part of the human microbiome as it helps in the breakdown of complex organic materials in the urogenital tract and other body sites. This metabolic versatility enables it to play a role in maintaining homeostasis within the microbial community. Furthermore, A. urogenitalis has been implicated in various human health conditions, particularly in cases of infections associated with the urogenital tract. Its presence in clinical specimens underscores the need for accurate identification in diagnostic microbiology, as it can be a marker for certain pathological states. Understanding this microbe's role in health and disease further emphasizes its importance in the study of human microbiota.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusActinomyces
SpeciesActinomyces urogenitalis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Actinomyces urogenitalis DSM 15434

Accession NumberACFH00000000.1

Gene Summary

Adenine Count

403573 bp

Thymine Count

413864 bp

Guanine Count

909427 bp

Cytosine Count

887153 bp

Genome Length

2614023 bp

Protein-coding Genes

2395 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
putative monovalent cation/h+ antiporter subunit fHMPREF0058_2366Not Available+2575754 - 257620615354.5
monovalent cation/proton antiporter, mnhg/phag subunitHMPREF0058_2367Not Available+2576203 - 257660113994.0
csbd-like proteinHMPREF0058_2368Not Available-2576707 - 25769047012.18
permease, cytosine/purine, uracil, thiamine, allantoin familyHMPREF0058_2369Not Available+2577118 - 257857549853.1
purine nucleoside phosphorylaseHMPREF0058_2370Not Available+2578578 - 257943829783.3
fumarate hydratase, class iiHMPREF0058_2371Q9RR70+2579610 - 258103150938.6
transporter, major facilitator family proteinHMPREF0058_2372Not Available+2581239 - 258253144845.3
carboxylesteraseHMPREF0058_2373D2D3B6+2582506 - 258404153478.3
transcriptional regulator, gntr familyHMPREF0058_2374Not Available-2584201 - 258482422741.3
hypothetical proteinHMPREF0058_2375Not Available-2584840 - 258534017478.2

Displaying genes 2421 – 2430 of 2458 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

352 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm00006985-dehydro-2-deoxy-D-gluconateC6H9O6Chemical structure of 5-dehydro-2-deoxy-D-gluconateNot available
Average177.133Da
Monoisotopic177.04046159Da

Displaying 1–10 of 352 metabolites