Streptococcus pneumoniae Hungary19A-6

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pneumoniae Hungary19A-6 is a Gram-positive, cocci-shaped bacterium that thrives in moderate temperatures, classified as a mesophile. This microbe is a heterotroph, relying on organic compounds for nutrition, and it exhibits facultative anaerobic behavior, meaning it can grow in both aerobic and anaerobic conditions. S. pneumoniae is predominantly found in the nasopharynx of humans but can also inhabit the lungs, middle ear, and, occasionally, the bloodstream. S. pneumoniae Hungary19A-6 is part of a larger group of bacteria known for their encapsulated strains, which provides enhanced virulence through immune evasion. The capsule plays a critical role in resisting phagocytosis, making it one of the major pathogenic forces behind pneumococcal diseases, including pneumonia, meningitis, and otitis media. The bacterium's cocci shape contributes to its characteristic formation in pairs (diplococci) or chains, which can be visually distinguished under a microscope following Gram staining. As a facultative anaerobe, S. pneumoniae can switch between aerobic metabolism, utilizing oxygen, and anaerobic fermentation when oxygen is scarce. This adaptability allows it to thrive in various environments within the human body. The strain Hungary19A-6 is particularly noteworthy for its antibiotic resistance patterns, which have implications for treatment strategies. Researchers continue to study this strain to understand its epidemiology and resistance mechanisms further, as it plays a significant role in public health. The development of vaccines targeting pneumococcal infections underscores the importance of addressing the pathogenic threat posed by S. pneumoniae.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pneumoniae
StrainHungary19A-6

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pneumoniae Hungary19A-6
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementPairs - Chains
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Streptococcus pneumoniae Hungary19A-6


Gene Summary

Adenine Count

682873 bp

Thymine Count

672784 bp

Guanine Count

448752 bp

Cytosine Count

441205 bp

Genome Length

2245615 bp

Protein-coding Genes

2152 genes

Non-Coding Genes

169 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+14975 - 14986Not Available
Gp254SPH_RS00125Q04N48+21969 - 2325547572.7
IntegraseSPH_RS00130Not Available-23497 - 2464544309.2
Hypothetical proteinSPH_RS12025Not Available-24816 - 2561630634.3
Putative repressor proteinSPH_RS00145Not Available-25743 - 2649829025.7
Orf049SPH_RS00150Not Available+26672 - 268787710.18
Gp14SPH_RS00155Not Available-27186 - 2786326067.1
Hypothetical proteinSPH_RS00160Q91FN5+27918 - 2863127099.2
Hypothetical proteinSPH_RS00165Not Available+28644 - 2890110044.1
AttlNot AvailableNot Available+28950 - 28964Not Available

Displaying genes 1 – 10 of 2321 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

96 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm0000719chloramphenicol 3-acetateC13H14Cl2N2O6Chemical structure of chloramphenicol 3-acetateNot available
Average365.16Da
Monoisotopic364.0228916Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–10 of 96 metabolites