Parabacteroides merdae ATCC 43184

Gram-negativeAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Tannerellaceae

Genus

Parabacteroides

Description

Parabacteroides merdae ATCC 43184 is a gram-negative, rod-shaped bacterium that thrives in anaerobic environments, making it an obligate anaerobe. This microbe typically prefers mesophilic temperature conditions, favoring growth in temperatures around 30-37 degrees Celsius. As a chemoheterotroph, P. merdae derives its energy from organic compounds, breaking them down for both carbon and energy sources. P. merdae is most commonly found in the gastrointestinal tract of humans, where it plays a significant role in the gut microbiome. The bacterium can also be located in various other body sites, including the oral cavity and the female genital tract, contributing to the overall microbial diversity in these environments. The presence of P. merdae in the gut is associated with complex interactions with other gut microbes, contributing to digestive health and potentially influencing host metabolism. One of the fascinating aspects of P. merdae is its capacity to participate in the degradation of complex carbohydrates and other organic compounds, helping in the fermentation process within the gut. This bacterium has also been the subject of research concerning its potential roles in human health and disease, including its relationship with conditions such as obesity and inflammatory bowel disease. Moreover, due to its genetic adaptability, Parabacteroides species, including P. merdae, are gaining interest for their potential use in probiotics and as therapeutic agents in microbiome-centered treatments. Its resilience in anaerobic conditions and ability to metabolize diverse substrates highlight its significant role in maintaining a balanced gut ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyTannerellaceae
GenusParabacteroides
SpeciesParabacteroides merdae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Parabacteroides merdae ATCC 43184

Accession NumberAAXE00000000.2

Gene Summary

Adenine Count

1214164 bp

Thymine Count

1209920 bp

Guanine Count

994085 bp

Cytosine Count

1013708 bp

Genome Length

4431877 bp

Protein-coding Genes

4384 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinPARMER_00025Not Available+25886 - 260114886.13
tonb-dependent receptorPARMER_00026Not Available+26176 - 2825779208.2
hypothetical proteinPARMER_00027Not Available+28297 - 2938240071.0
hypothetical proteinPARMER_00028Not Available+29395 - 3052242508.0
hypothetical proteinPARMER_00029Not Available-30551 - 307125967.23
hypothetical proteinPARMER_00030Not Available+30980 - 311175444.47
hypothetical proteinPARMER_00031Not Available-31191 - 313435552.66
hypothetical proteinPARMER_00032Not Available+31521 - 3268443828.7
tat pathway signal sequence domain proteinPARMER_00033Q9Y6N5-32777 - 3415351539.9
hypothetical proteinPARMER_00034Not Available-34349 - 3640678457.2

Displaying genes 31 – 40 of 2208 in total

Pathways

55 pathways

Metabolites

448 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm00007052-dehydro-3-deoxy-D-arabinonateC5H7O5Chemical structure of 2-dehydro-3-deoxy-D-arabinonateNot available
Average147.107Da
Monoisotopic147.0298969Da
BASm0000719chloramphenicol 3-acetateC13H14Cl2N2O6Chemical structure of chloramphenicol 3-acetateNot available
Average365.16Da
Monoisotopic364.0228916Da

Displaying 1–10 of 448 metabolites