Neisseria meningitidis 053442

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria meningitidis 053442 is a gram-negative, diplococcal-shaped microbe that thrives in mesophilic temperatures, categorizing it as a chemoheterotroph, and can be found in various body sites, including the respiratory tract, bloodstream, and cerebrospinal fluid, across multiple species, including humans. As an obligate aerobe, it requires oxygen to grow and survive. The gram-negative characteristic is attributed to its thin peptidoglycan layer and outer lipid membrane, which also makes it more resistant to certain antibiotics. Its diplococcal shape allows it to adhere to and invade host cells, contributing to its pathogenicity. As a mesophilic microbe, it grows best in moderate temperatures, typical of the human body.As a chemoheterotroph, Neisseria meningitidis 053442 relies on external sources of carbon and energy, which it obtains by breaking down complex organic molecules. This metabolic process allows it to thrive in various environments, including the human host. Its ability to infect multiple body sites, including the bloodstream and cerebrospinal fluid, makes it a significant concern for public health. The microbe's requirement for oxygen limits its growth to aerobic environments, which is why it is typically found in the upper respiratory tract, where oxygen levels are higher. Neisseria meningitidis 053442 is a major cause of meningitis and sepsis, particularly in children and young adults. Its ability to evade the host's immune system and cause severe disease has made it a focus of vaccine development and research. The microbe's polysaccharide capsule is a key virulence factor, allowing it to resist phagocytosis and cause invasive disease. Due to its severe disease potential and global distribution, Neisseria meningitidis 053442 is closely monitored by health organizations, and outbreaks are quickly contained through vaccination and contact tracing efforts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria meningitidis
Strain53442

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria meningitidis 053442
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementPairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Neisseria meningitidis 053442


Gene Summary

Adenine Count

520171 bp

Thymine Count

519922 bp

Guanine Count

558968 bp

Cytosine Count

554355 bp

Genome Length

2153416 bp

Protein-coding Genes

2062 genes

Non-Coding Genes

93 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Dna transposition proteinNMCC_RS05325Not Available+1009444 - 100992318336.2
EndolysinNMCC_RS05330Not Available+1010086 - 101063119295.0
hypothetical proteinNMCC_RS14665Not Available+1010628 - 10108016359.11
hypothetical proteinNMCC_RS14670Not Available+1010804 - 10109686227.33
hypothetical proteinNMCC_RS05345Not Available+1010971 - 10112078503.17
hypothetical proteinNMCC_RS05350Not Available+1011179 - 101160115418.7
hypothetical proteinNMCC_RS15240Not Available+1011498 - 101180310653.9
yegp family proteinNMCC_RS05360Q7DDI1-1011848 - 10120186403.57
hypothetical proteinNMCC_RS05365Not Available+1012031 - 10122498605.21
hypothetical proteinNMCC_RS05370Not Available+1012246 - 101257212227.6

Displaying genes 21 – 30 of 2155 in total

Pathways

3 pathways

Metabolites

120 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00005275-oxopentanoateC5H7O3Chemical structure of 5-oxopentanoateNot available
Average115.109Da
Monoisotopic115.040067665Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da

Displaying 1–10 of 120 metabolites