Campylobacter hominis ATCC BAA-381

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter hominis ATCC BAA-381 is a microbe that thrives in a mesophilic temperature range, specifically between 25°C and 37°C, placing it in the temperature preference category of "mesophilic". This microbe is a heterotroph, meaning it does not produce its own food, but rather obtains energy from the breakdown of organic compounds. C. hominis is also a chemoheterotroph, as it uses chemical energy from the oxidation of organic compounds to produce ATP. Gram-stained samples of C. hominis reveal a gram-negative staining pattern, indicating the presence of a thin peptidoglycan layer in the cell wall. The microbe's shape is typically spiral or comma-like, with a helical body and a flagellated phenotype. C. hominis can be found in various body sites, including the gastrointestinal tract, respiratory tract, and genitourinary tract, across all species. This microbe is an obligate aerobe, requiring the presence of oxygen for survival and growth. In terms of energy production, C. hominis is capable of using the Embden-Meyerhof-Parnas (EMP) pathway, also known as glycolysis, to produce ATP from glucose. This is in contrast to many other microbes that use different metabolic pathways, such as the pentose phosphate pathway or the citric acid cycle. One of the most distinctive features of C. hominis is its unique ability to infect humans, often causing gastrointestinal disease, particularly in individuals with compromised immune systems. Additionally, its ability to colonize various body sites, including the respiratory and genitourinary tracts, has significant implications for human health and disease. Despite being a relatively well-studied species, C. hominis remains a significant public health concern, and continued research is necessary to better understand its behavior and pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter hominis
StrainATCC BAA-381

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Campylobacter hominis ATCC BAA-381
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNo

Genome Summary

Campylobacter hominis ATCC BAA-381

Accession NumberNC_009714.1

Gene Summary

Adenine Count

584347 bp

Thymine Count

583884 bp

Guanine Count

272383 bp

Cytosine Count

270658 bp

Genome Length

1711273 bp

Protein-coding Genes

1614 genes

Non-Coding Genes

64 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
bifunctional adp-dependent nad(p)h-hydrate dehydratase/nad(p)h-hydrate epimeraseCHAB381_RS00125P56176+20699 - 2217153610.4
phosphoribosylglycinamide formyltransferaseCHAB381_RS00130P43846+22153 - 2273121416.4
hemolysin family proteinCHAB381_RS00135O07589+23014 - 2431849079.4
fumarate hydrataseCHAB381_RS00140Q58690+24346 - 2519130261.0
fe-s-containing hydro-lyaseCHAB381_RS00145Not Available+25202 - 2576219970.6
terc family proteinCHAB381_RS00150P43932+26381 - 2709726046.1
protoporphyrinogen oxidase hemjCHAB381_RS00155O26018+27130 - 2757317549.3
na+/h+ antiporter nhaaCHAB381_RS00160A7HZF9+27657 - 2884743591.8
6,7-dimethyl-8-ribityllumazine synthaseCHAB381_RS00165A7HZG0+28834 - 2930416834.5
transcription antitermination factor nusbCHAB381_RS00170A7HZG1+29306 - 2970115017.1

Displaying genes 41 – 50 of 1681 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

286 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00005275-oxopentanoateC5H7O3Chemical structure of 5-oxopentanoateNot available
Average115.109Da
Monoisotopic115.040067665Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da

Displaying 1–10 of 286 metabolites