Bifidobacterium breve UCC2003

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve UCC2003 is a Gram-positive, non-spore-forming bacterium that exhibits a rod-like shape and thrives in the mesophilic temperature range (optimal growth at approximately 37°C). As a chemoheterotroph, it derives its energy and carbon from organic compounds, specifically carbohydrates, and is categorized as an obligate anaerobe, meaning it requires an oxygen-free environment for growth and survival. Bifidobacterium breve UCC2003 is a member of the human gut microbiota and is primarily found in the intestines, particularly within the colon, where it plays a crucial role in maintaining gut health. It is also present in other sites in the body, including the oral cavity and female urogenital tract, showcasing its versatility in colonizing different niches. The bacterium is known for its probiotic properties, contributing to the fermentation of dietary fibers and the production of short-chain fatty acids, which are beneficial for gut epithelial health and overall metabolic processes. In addition to its role in digestion, Bifidobacterium breve UCC2003 has been studied for its potential health benefits, including modulation of the immune response, inhibition of pathogenic bacteria, and alleviation of gastrointestinal disorders such as diarrhea and irritable bowel syndrome. Current research is exploring its use in functional foods and dietary supplements aimed at enhancing gut flora balance and promoting overall health. The strain's genomic studies have revealed unique adaptations that facilitate its survival in the harsh intestinal environment, making it a focal point in probiotic research and applications.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgastro-intestinal (GI) tract
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve UCC2003

Accession NumberNC_020517.1

Gene Summary

Adenine Count

501258 bp

Thymine Count

498507 bp

Guanine Count

710416 bp

Cytosine Count

712503 bp

Genome Length

2422684 bp

Protein-coding Genes

2025 genes

Non-Coding Genes

72 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
IntegraseBBR_RS11980Not Available-440392 - 44121630335.5
AttrNot AvailableNot Available+447099 - 447113Not Available
chromosomal replication initiator protein dnaaBBR_RS10255Not Available+1 - 146754104.5
dna polymerase iii subunit betaBBR_RS10260Not Available+2043 - 316741025.6
dna replication/repair protein recfBBR_RS10265Not Available+3192 - 434942048.1
duf721 domain-containing proteinBBR_RS10270Not Available+4346 - 481617467.0
dna topoisomerase (atp-hydrolyzing) subunit bBBR_RS10275Not Available+4951 - 708978678.9
dna gyrase subunit aBBR_RS10280Not Available+7264 - 995499753.7
duf3566 domain-containing proteinBBR_RS10285Not Available+10023 - 1057419589.8
laci family dna-binding transcriptional regulatorBBR_RS10290Not Available-10649 - 1166237246.6

Displaying genes 11 – 20 of 2097 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

234 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000098D-cellotrioseC18H32O16Chemical structure of D-cellotrioseNot available
Average504.4371Da
Monoisotopic504.169035Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001418D-alluloseC6H12O6Chemical structure of D-allulose551-68-8
Average180.1559Da
Monoisotopic180.0633881Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da

Displaying 1–10 of 234 metabolites