Coprothermobacter proteolyticus DSM 5265

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Coprothermobacterota

Class

Coprothermobacteria

Order

Coprothermobacterales

Family

Coprothermobacteraceae

Genus

Coprothermobacter

Description

Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT) is a rod-shaped, anaerobic, thermophilic proteolytic, Gram-positive bacterium isolated from a thermophilic digestor that was fermenting tannery wastes and cattle manure. This organism was originally classified as Thermobacteroides proteolyticus and subsequently assigned to the new genus of Coprothermobacter. C. proteolyticus has an optimum temperature for growth of 63 degrees Celsius. It is phylogenetically related (96.3 % sequence similarity) to Coprothermobacter platensis (a moderately thermophilic bacterium), and both show similar morphology and fermentation products. Both can reduce thiosulfate to sulfide with glucose as substrate. The thiosulfate addition clearly stimulates glucose utilization and growth. Anaerobic digestion is increasingly used for carbon decontamination of agroindustrial wastewaters. Proteins are frequently a major component of'such wastes, and their degradation, initiated by extracellular proteases, is often incomplete. The vast majority of full-scale digestors are mesophilic, however thermophilic treatment is also being explored as it may have advantages, especially for effluents produced at high temperature (adapted from PubMed 9828430). (EBI Integr8)

Taxonomy

KingdomPseudomonadati
PhylumCoprothermobacterota
ClassCoprothermobacteria
OrderCoprothermobacterales
FamilyCoprothermobacteraceae
GenusCoprothermobacter
SpeciesCoprothermobacter proteolyticus
StrainDSM 5265

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Coprothermobacter proteolyticus DSM 5265
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature63
Temperature rangeThermophilic
HabitatSpecialized
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNo

Genome Summary

Coprothermobacter proteolyticus DSM 5265

Accession NumberNC_011295.1

Gene Summary

Adenine Count

395614 bp

Thymine Count

391363 bp

Guanine Count

323716 bp

Cytosine Count

314219 bp

Genome Length

1424912 bp

Protein-coding Genes

1419 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinCOPRO5265_RS00480Not Available+105315 - 10579117511.5
prepilin-type n-terminal cleavage/methylation domain-containing proteinCOPRO5265_RS00485Not Available+105797 - 10718549827.2
chemotaxis protein chewCOPRO5265_RS00490Not Available+107299 - 10772115651.2
diguanylate cyclaseCOPRO5265_RS00495Not Available-107708 - 110869120965.0
beta-n-acetylhexosaminidaseCOPRO5265_RS00500Not Available-110962 - 11222444997.4
imp dehydrogenaseCOPRO5265_RS00505Not Available+112481 - 11393852075.0
glutamine-hydrolyzing gmp synthaseCOPRO5265_RS00510Not Available+113946 - 11548156599.2
ferritin family proteinCOPRO5265_RS00515Not Available-116024 - 11650318545.8
gnat family n-acetyltransferaseCOPRO5265_RS00520Not Available-116510 - 11691415333.3
hypothetical proteinCOPRO5265_RS00525Not Available-116922 - 11798039060.9

Displaying genes 101 – 110 of 916 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

21 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002198beta-D-ribofuranoseC5H10O5Chemical structure of beta-D-ribofuranose50-69-1
Average150.1299Da
Monoisotopic150.05282343Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0003333(2R)-3-phosphoglycerateC3H4O7PChemical structure of (2R)-3-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm0003346(2R)-2-phosphoglycerateC3H4O7PChemical structure of (2R)-2-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm00033514-methyl-5-(2-phosphooxyethyl)-thiazoleC6H8NO4PSChemical structure of 4-methyl-5-(2-phosphooxyethyl)-thiazoleNot available
Average221.17Da
Monoisotopic220.9922631Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0003462(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinateC13H19N4O12PChemical structure of (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate3031-95-6
Average454.2833Da
Monoisotopic454.0737086Da

Displaying 1–10 of 21 metabolites