Legionella pneumophila subsp. pneumophila str. Philadelphia 1

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila is the causative agent of the Legionnaires' disease, a potentially fatal pneumonia. It was isolated after an outbreak of pneumonia at an American legion convention in Philadelphia. Legionella pneumophila is found in biofilms and fresh and industrial water systems worldwide. It can survive and replicate intracellularly in free-living protozoa, often in aquatic biofilms. Legionella pneumophila (strain Corby) is an aerobic human isolate. (HAMAP: LEGPC)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Pseudomonadota
Class	Gammaproteobacteria
Order	Legionellales
Family	Legionellaceae
Genus	Legionella
Species	Legionella pneumophila
Strain	Philadelphia 1

Profile

Physiology
Gram staining properties	Negative
Shape	Rod
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	Not Available
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens
Cell arrangement	Singles
Sporulation	Nonsporulating
Energy source	Chemoorganotroph
Pathogenicity	Yes

Genome Summary

Legionella pneumophila subsp. pneumophila str. Philadelphia 1

Accession NumberNC_002942.5

Gene Summary

Adenine Count

1048939 bp

Thymine Count

1048510 bp

Guanine Count

651691 bp

Cytosine Count

648613 bp

Genome Length

3397754 bp

Protein-coding Genes

2995 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

Name	Locus Tag	UniProt	Strand	Coordinates	Molecular Weight
aminopeptidase lapb	LPG_RS00155	Not Available	-	39042 - 40235	44723.1
hypothetical protein	LPG_RS00160	Not Available	-	40298 - 41323	37500.9
hypothetical protein	LPG_RS00165	Not Available	+	41587 - 42348	28578.0
hypothetical protein	LPG_RS00170	Not Available	+	42476 - 42832	12683.4
duf2490 domain-containing protein	LPG_RS00175	Not Available	-	42891 - 43613	28558.5
transporter substrate-binding domain-containing protein	LPG_RS00180	Not Available	-	43827 - 44570	28099.7
dot/icm t4ss effector ankq/lega10	LPG_RS00185	Not Available	-	44731 - 46254	58075.0
transporter suffix domain-containing protein	LPG_RS00190	Not Available	+	46512 - 46994	18701.9
metal-dependent hydrolase	LPG_RS00195	Not Available	-	47016 - 48011	37414.3
reprolysin-like metallopeptidase	LPG_RS00200	Not Available	+	48215 - 50431	80057.6

Displaying genes 31 – 40 of 3051 in total

Pathways

23 pathways

1,6-Anhydro-N-acetylmuramic Acid Recycling pathway thumbnail

1,6-Anhydro-N-acetylmuramic Acid Recycling

1,6-Anhydro-N-acetylmuramic Acid Recycling

Show All 23 Pathways

Metabolite ID	Metabolite name	Structure	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P		Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000251	2-dehydropantoateC6H9O4		Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000377	(S)-malateC4H4O5		Not available	Average132.0716Da Monoisotopic132.005873238Da
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6		Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0000401	(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8		Not available	Average286.218Da Monoisotopic286.0579371Da
BASm0001717	fumarateC4H2O4		Not available	Average114.0563Da Monoisotopic113.9953086Da
BASm0001779	orotateC5H3N2O4		Not available	Average155.09Da Monoisotopic155.0098302Da
BASm0001865	diphosphateHO7P2		Not available	Average174.95Da Monoisotopic174.9213971Da
BASm0001978	3-(4-hydroxyphenyl)pyruvateC9H7O4		Not available	Average179.1495Da Monoisotopic179.034433712Da
BASm0002157	7-cyano-7-deazaguanineC7H5N5O		Not available	Average175.1475Da Monoisotopic175.0494098Da

Displaying 1–10 of 163 metabolites