Clostridioides difficile 630

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Peptostreptococcales

Family

Peptostreptococcaceae

Genus

Clostridioides

Description

Clostridioides difficile 630 is a gram-positive, rod-shaped bacterium that thrives in anaerobic environments, characterized by its temperature preference for mesophilic conditions, within the range of 25-40°C. As a chemoheterotroph, it obtains its energy by breaking down organic compounds, specifically glycans, peptides, and proteins, in the absence of light. This microbe is an obligate anaerobe, requiring a low oxygen environment to survive, which is typical of many Clostridium species. Upon staining, C. difficile 630 exhibits a characteristic Gram-positive reaction, indicating a thick peptidoglycan layer in its cell wall. Its rod-shaped morphology, also known as a bacillus, is a defining feature of the genus Clostridium. In terms of its habitat, C. difficile 630 can be found colonizing the gastrointestinal tract of humans and animals, as well as other body sites, including the skin, respiratory tract, and genitourinary tract. This microbe's ability to produce energy is attributed to its fermentation process, where it converts glucose into lactate, acetate, and other short-chain fatty acids. This process is anaerobic, occurring in the absence of oxygen, which is typical of many anaerobic microbes. Despite its ability to thrive in anaerobic environments, C. difficile 630 has been linked to severe infections in humans, particularly in healthcare settings. The microbe's ability to adhere to epithelial cells and produce potent toxins, A and B, contributes to its pathogenic potential. Furthermore, the development of antibiotic resistance in C. difficile 630 has made treatment challenging, highlighting the importance of continued research and infection control measures. In addition to its importance in human health, C. difficile 630 has also been used as a model organism in research studies, particularly in the fields of microbiology, immunology, and infectious disease. Its ability to colonize the gastrointestinal tract and produce toxins has made it an important tool for studying the interactions between microbes and the host immune system.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderPeptostreptococcales
FamilyPeptostreptococcaceae
GenusClostridioides
SpeciesClostridioides difficile
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridioides difficile 630
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs-Singles-Chains
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Clostridioides difficile 630

Accession NumberNC_008226.2

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
single-stranded dna-binding proteinCD630_RS19035Not Available+4179603 - 41798308950.07
duf3298 and duf4163 domain-containing proteinCD630_RS19040Not Available-4180049 - 418079228977.0
class i sam-dependent methyltransferaseCD630_RS19045Not Available+4180960 - 418183233125.9
rlua family pseudouridine synthaseCD630_RS19050Not Available+4181832 - 418249725607.2
merr family transcriptional regulatorCD630_RS19055Not Available+4182518 - 418337533585.8
abc transporter permeaseCD630_RS19060Not Available-4183531 - 418604493084.3
abc transporter atp-binding proteinCD630_RS19065Not Available-4186077 - 418676325389.8
sensor histidine kinaseCD630_RS19070Not Available-4186846 - 418783537178.5
response regulator transcription factorCD630_RS19075Not Available-4187822 - 418850825379.8
hypothetical proteinCD630_RS20180Not Available-4188505 - 41886274696.68

Displaying genes 3871 – 3880 of 3981 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites