Clostridium acetobutylicum ATCC 824

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium acetobutylicum ATCC 824 is a gram-positive, rod-shaped bacterium that thrives in a thermophilic environment, falling under the category of " Mesophilic" temperature preference. As a chemoheterotroph, it relies on organic compounds as its energy source, where it uses fermentation as its mode of energy production. This means that C. acetobutylicum ATCC 824 does not require light for energy, and instead, breaks down organic molecules to produce ATP. The bacterium's gram-positive staining characteristics indicate the presence of a thick peptidoglycan cell wall, which provides structural support and protection against external environmental factors. Its rod-shaped morphology allows it to adapt to various environments and interact with its surroundings effectively. C. acetobutylicum ATCC 824 is an obligate anaerobe, meaning that it cannot thrive in the presence of oxygen and is susceptible to damage or even death from exposure to atmospheric oxygen. This adaptation enables it to survive in environments where oxygen levels are low or absent, such as soil, sediments, and the human gastrointestinal tract. In terms of body sites, C. acetobutylicum ATCC 824 can be found in various parts of the human body, including the gut, skin, and reproductive tract. It is also commonly isolated from soil, sewage, and industrial environments. One of the most notable features of C. acetobutylicum ATCC 824 is its ability to produce a wide range of bioactive compounds, including acetone, butanol, and ethanol, which are produced during fermentation. This microbe has been extensively studied in the context of industrial biofuel production, biotechnology, and bioremediation. Furthermore, C. acetobutylicum ATCC 824 has been found to possess genes involved in the biosynthesis of antimicrobial compounds, such as antimicrobial peptides and bacteriocins. These compounds have been shown to exhibit potent antimicrobial activity against other microorganisms, making this microbe a valuable subject for further research into antimicrobial resistance and the development of novel antibiotics.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium acetobutylicum
StrainATCC 824

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium acetobutylicum ATCC 824
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature10
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityNo

Genome Summary

Clostridium acetobutylicum ATCC 824

Accession NumberNC_001988.2

Gene Summary

Adenine Count

65546 bp

Thymine Count

67104 bp

Guanine Count

29118 bp

Cytosine Count

30232 bp

Genome Length

192000 bp

Protein-coding Genes

176 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
fad-binding oxidoreductaseCA_RS19430Not Available-42274 - 4357850560.4
hypothetical proteinCA_RS19435Not Available-43702 - 4469739323.2
glycosyltransferaseCA_RS19440Not Available-44778 - 4599846291.6
tetr/acrr family transcriptional regulatorCA_RS19445Not Available+46233 - 4679921986.3
ribonuclease zCA_RS19450Not Available-46802 - 4754827667.7
methyl-accepting chemotaxis proteinCA_RS19455Not Available+47893 - 4904141653.8
transcriptional regulatorCA_RS19460Not Available-49110 - 492264720.04
mfs transporterCA_RS19465Not Available-49363 - 5058943887.1
carboxylesterase/lipase family proteinCA_RS19470Not Available+50765 - 5225855905.6
sdr family nad(p)-dependent oxidoreductaseCA_RS19475Not Available-52305 - 5302727061.3

Displaying genes 41 – 50 of 3992 in total

Pathways

3 pathways

Metabolites

3 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0017258Acetoacetic acidC4H6O3Chemical structure of Acetoacetic acid541-50-4
Average102.0886Da
Monoisotopic102.031694058Da
BASm0019245 (2Z)-2-aminobut-2-enoateC4H6NO2Chemical structure of (2Z)-2-aminobut-2-enoateNULL
Average100.098Da
Monoisotopic100.040402017Da

Displaying 1–3 of 3 metabolites