Methylobacillus flagellatus KT

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Nitrosomonadales

Family

Methylophilaceae

Genus

Methylobacillus

Description

Methylobacillus flagellatus strain KT. This organism contains multiple formaldehyde degradation pathways including a ribulose monophosphate (RMP) cycle and a linear pathway utilizing tetrahydromethanopterin-dependent enzymes. Degradation of formaldehydge is part of the process of incorporating carbon into the cell, and as this organism is an obligate methylotroph and can only utilize methanol and methylamine as the sole carbon and energy sources, conversion of intermediates is both an important part of the growth of cell and an exploitable process for industrial purposes. This strain was isolated from activated sludge found at the wastewater treatment plant in Moscow, Russia and is the fastest growing methylotroph discovered. The fast growth and conversion rate make it useful in industrial production of biomolecules. (NCBI BioProject: bp_list[1])

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNitrosomonadales
FamilyMethylophilaceae
GenusMethylobacillus
SpeciesMethylobacillus flagellatus
StrainKT

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Methylobacillus flagellatus KT
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatSpecialized
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNo

Genome Summary

Methylobacillus flagellatus KT

Accession NumberNC_007947.1

Gene Summary

Adenine Count

656439 bp

Thymine Count

659376 bp

Guanine Count

826742 bp

Cytosine Count

828960 bp

Genome Length

2971517 bp

Protein-coding Genes

2785 genes

Non-Coding Genes

92 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
uroporphyrinogen-iii c-methyltransferaseMFLA_RS00160Not Available-32549 - 3364041273.3
uroporphyrinogen-iii synthaseMFLA_RS00165Not Available-33633 - 3440328067.1
hydroxymethylbilane synthaseMFLA_RS00170Not Available-34442 - 3537432966.8
lytr/algr family response regulator transcription factorMFLA_RS00175Not Available-35473 - 3621928078.2
sensor histidine kinaseMFLA_RS00180Not Available-36216 - 3723838156.2
argininosuccinate lyaseMFLA_RS00185Not Available+37294 - 3870051866.1
ggdef domain-containing proteinMFLA_RS00190Not Available-38751 - 4031658536.5
radical sam family heme chaperone hemwMFLA_RS00195Not Available-40461 - 4161542987.1
hypothetical proteinMFLA_RS00200Not Available-41647 - 418808928.39
rdgb/ham1 family non-canonical purine ntp pyrophosphataseMFLA_RS00205Not Available-41877 - 4248221714.9

Displaying genes 91 – 100 of 2877 in total

Pathways

23 pathways
1,6-Anhydro-N-acetylmuramic Acid Recycling pathway thumbnail
1,6-Anhydro-N-acetylmuramic Acid Recycling
1,6-Anhydro-N-acetylmuramic Acid Recycling
Show All 23 Pathways

Metabolites

158 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0001921(S)-3-methyl-2-oxopentanoateC6H9O3Chemical structure of (S)-3-methyl-2-oxopentanoate1460-34-0
Average129.1339Da
Monoisotopic129.0551692Da
BASm00021577-cyano-7-deazaguanineC7H5N5OChemical structure of 7-cyano-7-deazaguanineNot available
Average175.1475Da
Monoisotopic175.0494098Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da

Displaying 1–10 of 158 metabolites