Burkholderia mallei ATCC 23344

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia mallei is the etiologic agent of glanders, a disease that is often fatal. Its natural reservoir are horses and other equines, but it can be occasionally transmitted to humans either by inhalation or through breaks in the skin. It is an obligate animal pathogen, with an intracellular localization. B. mallei is highly infectious as an aerosol and was used as a biological weapon in the American Civil War and in both World Wars. Unlike the related bacterium B.pseudomallei it is non-motile. One of its virulence factors has been identified as the type III secretion system, another as the newly characterized type VI (T6S). Strain NCTC 10229 will be used for comparative genomics. (EBI Integr8)

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia mallei
StrainATCC 23344

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Burkholderia mallei ATCC 23344
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Burkholderia mallei ATCC 23344

Accession NumberNC_006348.1

Gene Summary

Adenine Count

559281 bp

Thymine Count

558552 bp

Guanine Count

1185888 bp

Cytosine Count

1206427 bp

Genome Length

3510148 bp

Protein-coding Genes

3222 genes

Non-Coding Genes

55 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
iclr family transcriptional regulatorBMA_RS00340Not Available+85184 - 8613734181.1
duf3108 domain-containing proteinBMA_RS00345Not Available+86216 - 8753545874.7
duf3567 domain-containing proteinBMA_RS00350Not Available+87718 - 879759750.52
homocysteine s-methyltransferase family proteinBMA_RS00355Not Available+88163 - 8924238490.8
methionine synthaseBMA_RS00360Not Available+89288 - 9200599412.3
is1182-like element isbma2 family transposaseBMA_RS00365Not Available+92272 - 9373556045.2
duf1840 domain-containing proteinBMA_RS00370Not Available-93841 - 9416411753.9
arginine--trna ligaseBMA_RS00375Not Available+94367 - 9615164581.6
spor domain-containing proteinBMA_RS00380Not Available+96230 - 9707828876.8
thiol:disulfide interchange protein dsbaBMA_RS00385Not Available+97130 - 9776823386.2

Displaying genes 71 – 80 of 5292 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

479 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000198tetracenomycin CC23H20O11Chemical structure of tetracenomycin CNot available
Average472.402Da
Monoisotopic472.100561464Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da

Displaying 1–10 of 479 metabolites