Akkermansia muciniphila str. CBA5201

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila str. CBA5201 is a Gram-negative, anaerobic bacterium characterized by its cocci shape, which typically arranges in pairs or singles. This strain thrives optimally at a temperature of 37.0°C, reflecting its adaptation to host-associated environments. Akkermansia muciniphila is known for its role in the gut microbiota, where it contributes to the degradation of mucin, a key component of the intestinal mucus layer. As an anaerobe, A. muciniphila str. CBA5201 is well-suited to the low-oxygen conditions prevalent in the gastrointestinal tract, allowing it to thrive in this niche while potentially influencing host health through its metabolic activities. Notably, its presence in the gut microbiome may play a crucial role in maintaining the integrity of the mucosal barrier, suggesting its involvement in the host's immune response and overall metabolic homeostasis. The unique ability of Akkermansia muciniphila to utilize mucin as a carbon source underscores its potential significance in the modulation of gut health and its impact on host-microbe interactions. Further exploration of its functional capacity may provide insights into its contributions to gut ecology and its implications for host well-being.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. CBA5201
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila str. CBA5201

Accession NumberNZ_CP033388.1

Gene Summary

Adenine Count

641282 bp

Thymine Count

636655 bp

Guanine Count

789726 bp

Cytosine Count

792744 bp

Genome Length

2860407 bp

Protein-coding Genes

2366 genes

Non-Coding Genes

66 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
pfkb family carbohydrate kinaseAKKM5201_RS02735Not Available-603915 - 60540554420.4
30s ribosomal protein s21AKKM5201_RS02740Not Available+605634 - 6058859704.57
glutamate-1-semialdehyde 2,1-aminomutaseAKKM5201_RS02745Not Available+605970 - 60725046347.7
ankyrin repeat domain-containing proteinAKKM5201_RS02750Not Available+607303 - 60836138930.9
mfs transporterAKKM5201_RS02755Not Available-608580 - 61054170701.5
hypothetical proteinAKKM5201_RS02760Not Available-610864 - 61239655933.4
glutamine--trna ligase/yqey domain fusion proteinAKKM5201_RS02765Not Available+612892 - 61457164174.1
bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/gtp cyclohydrolase iiAKKM5201_RS02770Not Available+614591 - 61579343774.0
6,7-dimethyl-8-ribityllumazine synthaseAKKM5201_RS02775Not Available+615813 - 61630117910.8
transcription antitermination factor nusbAKKM5201_RS02780Not Available+616330 - 61721433283.8

Displaying genes 551 – 560 of 2432 in total

Pathways

23 pathways

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites