Bacillus subtilis subsp. subtilis str. 168

Gram-positiveRodMotileFacultative aerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Bacillaceae

Genus

Bacillus

Description

Bacillus subtilis subsp. subtilis str. 168 is a Gram-positive, rod-shaped bacterium that thrives optimally at moderate temperatures, classifying it as a mesophile. This organism is a heterotroph, obtaining its organic carbon from the breakdown of various substrates, and is categorized as a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments.As a member of the Bacillus genus, B. subtilis str. 168 exhibits resilience and adaptability, frequently found in soil and plant surfaces, as well as within the gastrointestinal tracts of various animals. Its rod-like shape allows for efficient movement and colonization in diverse environments. The Gram-positive nature of this bacterium is indicative of its thick peptidoglycan cell wall, which provides structural integrity and resistance against environmental stresses. This strain has been extensively studied and utilized in biotechnology due to its capacity for producing enzymes, antibiotics, and bioactive compounds. One of the standout traits of B. subtilis is its ability to form endospores, enabling it to survive harsh environmental conditions, including extreme temperatures, desiccation, and nutrient depletion. The endospore formation process not only facilitates survival but also plays a crucial role in its life cycle and ecological resilience. Bacillus subtilis subsp. subtilis str. 168 serves as a model organism in molecular biology, contributing significantly to our understanding of cellular processes and genetic regulation. Its genome has been fully sequenced, allowing researchers to manipulate its genetic material for various practical applications, such as biofertilizers and probiotics in food production. This microorganism also holds promise in sustainable agriculture, enhancing soil health and plant growth while minimizing reliance on chemical fertilizers.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyBacillaceae
GenusBacillus
SpeciesBacillus subtilis
Strain168

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Bacillus subtilis subsp. subtilis str. 168
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative aerobe
Optimal temperature25
Temperature rangeMesophilic
HabitatTerrestrial
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationSporulating
Energy sourceNot Available
PathogenicityNo

Genome Summary

Bacillus subtilis subsp. subtilis str. 168

Accession NumberNC_000964.3

Gene Summary

Adenine Count

1188073 bp

Thymine Count

1193137 bp

Guanine Count

915112 bp

Cytosine Count

919284 bp

Genome Length

4215606 bp

Protein-coding Genes

3981 genes

Non-Coding Genes

379 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
thiamine-phosphate pyrophosphorylase (thiamine phosphate synthase)BSU_38290Not Available-3930707 - 393137523682.4
5-(2-hydroxyethyl)-4-methylthiazole kinaseBSU_38300Not Available-3931372 - 393219028214.9
transcriptional regulator (lysr family, cidab expression)BSU_38310Not Available-3932198 - 393310334679.0
metabolic regulator of murein hydrolasesBSU_38320Not Available+3933209 - 393359514262.4
metabolic regulator controlling activity of murein hydrolasesBSU_38330Not Available+3933577 - 393425423888.3
putative sugar permeaseBSU_38340Not Available+3934358 - 393555744011.8
hypothetical proteinBSU_38350Not Available+3935591 - 39357887227.74
large subunit ribosomal rna m5c1962 methyltransferaseBSU_38360Not Available-3935824 - 393701444446.2
glyoxalase iBSU_38370Not Available+3937135 - 393751514434.1
hypothetical proteinBSU_38380Not Available-3937553 - 393823025863.6

Displaying genes 4071 – 4080 of 4362 in total

Pathways

20 pathways

Metabolites

22 records
Metabolite IDMetabolite nameStructureCAS number
BASm00006985-dehydro-2-deoxy-D-gluconateC6H9O6Chemical structure of 5-dehydro-2-deoxy-D-gluconateNot available
Average177.133Da
Monoisotopic177.04046159Da
BASm0001086scyllo-inososeC6H10O6Chemical structure of scyllo-inososeNot available
Average178.14Da
Monoisotopic178.0477381Da
BASm00015513D-3,5/4-trihydroxycyclohexane-1,2-dioneC6H8O5Chemical structure of 3D-3,5/4-trihydroxycyclohexane-1,2-dioneNot available
Average160.125Da
Monoisotopic160.0371734Da
BASm0002319Cu(+)CuChemical structure of Cu(+)7440-50-8
Average63.546Da
Monoisotopic62.92960108Da
BASm0002396scyllo-inosineC6H10O6Chemical structure of scyllo-inosineNot available
Average178.14Da
Monoisotopic178.047738042Da
BASm00037505-deoxy-D-glucuronateC6H9O6Chemical structure of 5-deoxy-D-glucuronateNot available
Average177.133Da
Monoisotopic177.04046159Da
BASm0004428UDP-N-acetylbacillosamineC17H27N4O15P2Chemical structure of UDP-N-acetylbacillosamineNot available
Average589.364Da
Monoisotopic589.0953638Da
BASm0014031Butyric acidC4H8O2Chemical structure of Butyric acid107-92-6
Average88.1051Da
Monoisotopic88.0524295Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014042Oxoglutaric acidC5H6O5Chemical structure of Oxoglutaric acid328-50-7
Average146.0981Da
Monoisotopic146.021523302Da

Displaying 1–10 of 22 metabolites