Staphylococcus aureus subsp. aureus MW2

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus aureus subsp. aureus MW2 is a gram-positive cocci bacterium that exhibits a staphylococcal arrangement, thrives optimally at temperatures around 37°C, is classified as a chemoheterotroph, and is a facultative anaerobe. This versatile microbe typically colonizes human skin and mucosal surfaces, including the nose, throat, and genitourinary tract, while also being associated with various infections in multiple body sites such as wounds, the bloodstream, respiratory tract, and bones. As a gram-positive organism, S. aureus MW2 retains crystal violet during the Gram staining process, resulting in a purple coloration indicative of its thick peptidoglycan cell wall. Its cocci shape allows for its characteristic formation into clusters, resembling bunches of grapes, which is a hallmark of staphylococci. The optimal growth temperature aligns with the human body temperature, facilitating its survival and proliferation within the host. Being a chemoheterotroph, S. aureus MW2 relies on organic compounds for both energy and carbon, which it derives from various substrates in its environment. This metabolic flexibility enables it to thrive in diverse environments, whether on skin or in other nutrient-rich niches. As a facultative anaerobe, it can grow in the presence or absence of oxygen, allowing it to switch between aerobic and anaerobic respiration based on environmental conditions. S. aureus MW2 is particularly noteworthy due to its ability to produce a wide array of virulence factors, including toxins and enzymes, which contribute to its pathogenicity. It is also known for its resistance to many antibiotics, making infections caused by this strain challenging to treat. The emergence of MRSA (Methicillin-resistant Staphylococcus aureus) strains, including MW2, raises significant public health concerns as these infections can lead to severe medical complications. Understanding this bacterium's behavior and resistance mechanisms is crucial for effective treatment and prevention strategies.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus aureus
StrainMW2

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Staphylococcus aureus subsp. aureus MW2
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Staphylococcus aureus subsp. aureus MW2

Accession NumberNC_003923.1

Gene Summary

Adenine Count

942249 bp

Thymine Count

952267 bp

Guanine Count

463710 bp

Cytosine Count

462236 bp

Genome Length

2820462 bp

Protein-coding Genes

2560 genes

Non-Coding Genes

239 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
glycerophosphoryl diester phosphodiesteraseMW_RS00155Not Available+38288 - 3903127901.1
maoc family dehydrataseMW_RS00160Not Available+39128 - 3955616137.3
pbp2a family beta-lactam-resistant peptidoglycan transpeptidase mecaMW_RS00165Not Available-39602 - 4161176237.9
beta-lactam sensor/signal transducer mecr1MW_RS00170Not Available+41708 - 4269438131.3
type i restriction enzyme endonuclease domain-containing proteinMW_RS00175Not Available+42666 - 429269924.04
imidazole glycerol phosphate synthase subunit hisfMW_RS00180Not Available-42917 - 4452464043.6
duf1643 domain-containing proteinMW_RS00185Not Available-44576 - 4508219419.8
duf960 family proteinMW_RS00190Not Available-45097 - 4540812621.0
saugi family uracil-dna glycosylase inhibitorMW_RS00195Not Available-45495 - 4584513787.2
cassette chromosome recombinase ccrbMW_RS00200Not Available-46367 - 4799562772.6

Displaying genes 201 – 210 of 2799 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites