Clostridium perfringens str. 13

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium perfringens str. 13 is a Gram-positive, rod-shaped bacterium that thrives in anaerobic environments, demonstrating a preference for mesophilic temperatures, making it active between 20°C and 45°C. As a heterotroph, it obtains its nutrients by decomposing organic matter, primarily carbohydrates and proteins. This microbe is predominantly found in the gastrointestinal tracts of various animals, including humans, and can also inhabit soil, sediments, and decaying organic material. The Gram-positive nature of C. perfringens str. 13 is characterized by a thick peptidoglycan layer in its cell wall, which contributes to its resilience in harsh conditions. Its rod-like shape allows for efficient movement and colonization in nutrient-rich environments, making it capable of rapid growth under suitable conditions. As a mesophilic organism, it adapts well to body temperatures, which is particularly significant for its role in human and animal health. C. perfringens str. 13 is classified as an obligate anaerobe, meaning it cannot survive in the presence of oxygen. This characteristic is crucial for its pathogenicity, as it thrives in the anaerobic environments of deep tissue infections, such as gas gangrene, where it produces potent toxins. Its heterotrophic metabolism enables it to efficiently utilize the nutrients available in host tissues. In addition to its role in human disease, Clostridium perfringens is also notable for its ability to produce spores that can survive extreme environmental conditions. These spores can lead to foodborne illness, particularly in improperly cooked meats, emphasizing the importance of food safety practices. The microbe's diverse metabolic capabilities and ecological versatility underline its significance in both health and environmental contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium perfringens
Strain13

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium perfringens str. 13
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementSingles - Pairs - Chains
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Clostridium perfringens str. 13

Accession NumberNC_003366.1

Gene Summary

Adenine Count

1060154 bp

Thymine Count

1105316 bp

Guanine Count

419228 bp

Cytosine Count

446732 bp

Genome Length

3031430 bp

Protein-coding Genes

2626 genes

Non-Coding Genes

147 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hlyc/corc family transporterCPE_RS00470Not Available+43192 - 4445747451.5
nucleoside deaminaseCPE_RS00475Not Available+44460 - 4489115972.3
hypothetical proteinCPE_RS00480Not Available+44954 - 4541218032.9
duf2809 domain-containing proteinCPE_RS00485Not Available+45536 - 4590114333.3
glucosaminidase domain-containing proteinCPE_RS00490Not Available+46011 - 4667324406.8
protein adenylyltransferase seloCPE_RS00495Not Available-46787 - 4825955808.2
alpha-toxinCPE_RS00500Not Available+48590 - 4978645531.8
cobw family gtp-binding proteinCPE_RS00505Not Available+49974 - 5090035161.7
gtp-binding proteinCPE_RS00510Not Available+50920 - 5150422348.6
permeaseCPE_RS00515Not Available+51507 - 5240032497.0

Displaying genes 61 – 70 of 2830 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

313 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm00006985-dehydro-2-deoxy-D-gluconateC6H9O6Chemical structure of 5-dehydro-2-deoxy-D-gluconateNot available
Average177.133Da
Monoisotopic177.04046159Da
BASm0000719chloramphenicol 3-acetateC13H14Cl2N2O6Chemical structure of chloramphenicol 3-acetateNot available
Average365.16Da
Monoisotopic364.0228916Da

Displaying 1–10 of 313 metabolites