Clostridium perfringens str. 13

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium perfringens str. 13 is a Gram-positive, rod-shaped bacterium that thrives in anaerobic environments, demonstrating a preference for mesophilic temperatures, making it active between 20°C and 45°C. As a heterotroph, it obtains its nutrients by decomposing organic matter, primarily carbohydrates and proteins. This microbe is predominantly found in the gastrointestinal tracts of various animals, including humans, and can also inhabit soil, sediments, and decaying organic material. The Gram-positive nature of C. perfringens str. 13 is characterized by a thick peptidoglycan layer in its cell wall, which contributes to its resilience in harsh conditions. Its rod-like shape allows for efficient movement and colonization in nutrient-rich environments, making it capable of rapid growth under suitable conditions. As a mesophilic organism, it adapts well to body temperatures, which is particularly significant for its role in human and animal health. C. perfringens str. 13 is classified as an obligate anaerobe, meaning it cannot survive in the presence of oxygen. This characteristic is crucial for its pathogenicity, as it thrives in the anaerobic environments of deep tissue infections, such as gas gangrene, where it produces potent toxins. Its heterotrophic metabolism enables it to efficiently utilize the nutrients available in host tissues. In addition to its role in human disease, Clostridium perfringens is also notable for its ability to produce spores that can survive extreme environmental conditions. These spores can lead to foodborne illness, particularly in improperly cooked meats, emphasizing the importance of food safety practices. The microbe's diverse metabolic capabilities and ecological versatility underline its significance in both health and environmental contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium perfringens
Strain13

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium perfringens str. 13
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementSingles - Pairs - Chains
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Clostridium perfringens str. 13


Gene Summary

Adenine Count

1060154 bp

Thymine Count

1105316 bp

Guanine Count

419228 bp

Cytosine Count

446732 bp

Genome Length

3031430 bp

Protein-coding Genes

2626 genes

Non-Coding Genes

147 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
rip metalloprotease rsepCPE_RS08725Not Available-1971899 - 197290636493.4
1-deoxy-d-xylulose-5-phosphate reductoisomeraseCPE_RS08730Not Available-1972918 - 197407243224.7
phosphatidate cytidylyltransferaseCPE_RS08735Not Available-1974432 - 197522629452.0
isoprenyl transferaseCPE_RS08740Not Available-1975244 - 197600529260.2
ribosome recycling factorCPE_RS08745Not Available-1976070 - 197662720926.6
ump kinaseCPE_RS08750Not Available-1976641 - 197735425786.2
translation elongation factor tsCPE_RS08755Not Available-1977447 - 197835833189.1
30s ribosomal protein s2CPE_RS08760Not Available-1978438 - 197913926333.9
gtp-sensing pleiotropic transcriptional regulator codyCPE_RS08765Not Available-1979521 - 198029728547.9
type i dna topoisomeraseCPE_RS08770Not Available-1980439 - 198254180230.2

Displaying genes 1731 – 1740 of 2830 in total

Metabolites

1891 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da

Displaying 1–10 of 1891 metabolites