Streptococcus cristatus

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus cristatus is a Gram-positive, spherical-shaped microbe that thrives in the mesophilic temperature range of 25-40°C, indicating a preference for moderate temperatures. As a chemoheterotroph, this microbe obtains its energy by breaking down organic compounds, relying on external sources of carbon and energy. Its metabolism is characterized by the production of ATP through cellular respiration, primarily relying on the citric acid cycle and oxidative phosphorylation. Streptococcus cristatus is distributed throughout various body sites, including the skin, respiratory, gastrointestinal, and genitourinary tracts, as well as the oral cavity, making it a ubiquitous inhabitant of the human host. As an obligate aerobe, this microbe requires the presence of oxygen to survive and grow, which is consistent with its ability to tolerate high levels of oxygen and thrive in aerobic environments. Physically, Streptococcus cristatus presents as small, non-motile, spherical cells that typically range in diameter from 0.5-1.5 μm. Under the Gram stain, its cell walls exhibit a characteristic blue color due to the presence of peptidoglycan, which is a key component of bacterial cell walls. Notably, Streptococcus cristatus has been linked to various diseases, such as upper respiratory tract infections, skin infections, and endocarditis. Additionally, it has been used as a model organism for studying bacterial communication and biofilm formation, providing valuable insights into the complex interactions between microorganisms and their hosts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus cristatus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbronchoalveolar lavage fluid; mucosal surfaces of the oral cavity; oral cavity; oral mucosa; oral mucosa microbiota; tumor tissue
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementChains
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus cristatus


Gene Summary

Adenine Count

581471 bp

Thymine Count

580211 bp

Guanine Count

454501 bp

Cytosine Count

410360 bp

Genome Length

2026543 bp

Protein-coding Genes

1924 genes

Non-Coding Genes

80 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
exodeoxyribonucleaseTW70_00917P0A2X3-941562 - 94238931152.6
methionyl-trna synthetaseTW70_00918P67580+942579 - 94457675405.0
hypothetical proteinTW70_00919Not Available+944754 - 9448884862.57
hypothetical proteinTW70_00920Not Available+944893 - 94554924910.2
hypothetical proteinTW70_00921Not Available-945655 - 94688146506.4
natural resistance-associated macrophage proteinTW70_00922P57864-947002 - 94826145602.8
dna-binding response regulatorTW70_00923Q6GJ11+948467 - 94915326286.1
sensor histidine kinaseTW70_00924Q45614+949137 - 95011737876.3
trax proteinTW70_00925Not Available+950229 - 95098728832.2
abc transporter atp-binding proteinTW70_00926Not Available+951071 - 95185028873.8

Displaying genes 921 – 930 of 3987 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

268 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001086scyllo-inososeC6H10O6Chemical structure of scyllo-inososeNot available
Average178.14Da
Monoisotopic178.0477381Da
BASm0001140cyclohexyl isocyanideC7H11NChemical structure of cyclohexyl isocyanideNot available
Average109.1689Da
Monoisotopic109.089149357Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da

Displaying 1–10 of 268 metabolites