Burkholderia mallei

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia mallei is a Gram-negative, rod-shaped bacterium that is primarily associated with host organisms. This microbe is an obligate aerobe, meaning it requires oxygen for its growth and metabolism. As a member of the Burkholderia genus, B. mallei is notably adapted to a host-associated environment, which may influence its interactions with both the host and the surrounding microbial community. The habitat of B. mallei is significant as it underscores the bacterium's specialized adaptations for survival and proliferation in a host. This adaptation may facilitate its ability to exploit host resources while also navigating the complex immune responses elicited by the host organism. The pathogenic potential of B. mallei, associated with glanders disease in equines, further highlights its ecological niche and the implications of host-associated lifestyles in microbial evolution. In terms of ecological insight, B. mallei's existence as a strictly aerobic organism suggests a competitive advantage in oxygen-rich environments, enabling it to outcompete other microorganisms that may inhabit similar niches. This adaptation may influence the dynamics of microbial communities within the host, potentially affecting host health and disease outcomes. Overall, the traits of Burkholderia mallei reflect its specialized role within host ecosystems and underline the intricate relationships between pathogens and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia mallei
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Burkholderia mallei
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Burkholderia mallei

Accession NumberRKJX00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

5832 genes

Non-Coding Genes

70 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
hypothetical proteinEGT66_00015Not Available+1576 - 18369722.91
hypothetical proteinEGT66_00020Not Available-1791 - 236021229.9
porinEGT66_00025Not Available+2699 - 323819158.0
is3 family transposaseEGT66_00030Not Available+3138 - 425742632.3
hypothetical proteinEGT66_00035Not Available+4279 - 479418885.3
hypothetical proteinEGT66_00040Not Available+5251 - 563113718.4
alkaline phosphataseEGT66_00045Not Available+5922 - 736149558.5
alkaline phosphataseEGT66_00050Not Available+7394 - 879748618.4
hypothetical proteinEGT66_00055Not Available+8827 - 963928788.7
hypothetical proteinEGT66_00060Not Available+9739 - 99577741.61

Displaying genes 1 – 10 of 5902 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm0003335L-glutamyl 5-phosphateC5H8NO7PChemical structure of L-glutamyl 5-phosphateNot available
Average225.094Da
Monoisotopic225.0049358Da
BASm00033374-hydroxy-4-methyl-2-oxoglutarateC6H6O6Chemical structure of 4-hydroxy-4-methyl-2-oxoglutarateNot available
Average174.109Da
Monoisotopic174.0175351Da
BASm0003346(2R)-2-phosphoglycerateC3H4O7PChemical structure of (2R)-2-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm00034237-phospho-2-dehydro-3-deoxy-D-arabino-heptonateC7H10O10PChemical structure of 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonateNot available
Average285.122Da
Monoisotopic285.0028043Da
BASm00034561-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamideC15H21N5O15P2Chemical structure of 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamideNot available
Average573.2993Da
Monoisotopic573.0509381Da
BASm0003491(2S)-2-acetolactateC5H7O4Chemical structure of (2S)-2-acetolactateNot available
Average131.108Da
Monoisotopic131.0349823Da
BASm00034972-C-methyl-D-erythritol 2,4-cyclic diphosphateC5H10O9P2Chemical structure of 2-C-methyl-D-erythritol 2,4-cyclic diphosphate143488-44-2
Average276.075Da
Monoisotopic275.9800049Da
BASm00035255-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamideC15H21N5O15P2Chemical structure of 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamideNot available
Average573.303Da
Monoisotopic573.0531333Da
BASm0003657N-acetyl-D-muramate 6-phosphateC11H17NO11PChemical structure of N-acetyl-D-muramate 6-phosphateNot available
Average370.228Da
Monoisotopic370.0555681Da

Displaying 31–40 of 88 metabolites