Burkholderia mallei

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia mallei is a Gram-negative, rod-shaped bacterium that is primarily associated with host organisms. This microbe is an obligate aerobe, meaning it requires oxygen for its growth and metabolism. As a member of the Burkholderia genus, B. mallei is notably adapted to a host-associated environment, which may influence its interactions with both the host and the surrounding microbial community. The habitat of B. mallei is significant as it underscores the bacterium's specialized adaptations for survival and proliferation in a host. This adaptation may facilitate its ability to exploit host resources while also navigating the complex immune responses elicited by the host organism. The pathogenic potential of B. mallei, associated with glanders disease in equines, further highlights its ecological niche and the implications of host-associated lifestyles in microbial evolution. In terms of ecological insight, B. mallei's existence as a strictly aerobic organism suggests a competitive advantage in oxygen-rich environments, enabling it to outcompete other microorganisms that may inhabit similar niches. This adaptation may influence the dynamics of microbial communities within the host, potentially affecting host health and disease outcomes. Overall, the traits of Burkholderia mallei reflect its specialized role within host ecosystems and underline the intricate relationships between pathogens and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia mallei
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Burkholderia mallei
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Burkholderia mallei

Accession NumberRKJX00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

5832 genes

Non-Coding Genes

70 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
copper homeostasis protein cutcEGT66_00065Not Available+10018 - 1073124289.2
biotin synthase biobEGT66_00070Not Available-10858 - 1187737017.2
atp-dependent dethiobiotin synthetase biodEGT66_00075Not Available-11941 - 1266324875.2
8-amino-7-oxononanoate synthaseEGT66_00080Not Available-12660 - 1384440701.5
adenosylmethionine--8-amino-7-oxononanoate transaminaseEGT66_00085Not Available-13841 - 1518749317.6
hypothetical proteinEGT66_00090Not Available-15751 - 1703445372.1
hypothetical proteinEGT66_00095Not Available-17263 - 1771516425.2
sdr family oxidoreductaseEGT66_00100Not Available-17747 - 1843023616.6
acetyl-coa c-acyltransferaseEGT66_00105Not Available-18461 - 1965440917.5
carbonate dehydrataseEGT66_00110Not Available-19641 - 2041128231.6

Displaying genes 11 – 20 of 5902 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm00191503b-AllotetrahydrocortisolC19H35N5O6SeChemical structure of 3b-AllotetrahydrocortisolNULL
Average508.489Da
Monoisotopic509.175256Da
BASm0019927(S)-Ureidoglycolic acidC3H6N2O4Chemical structure of (S)-Ureidoglycolic acid7424-03-5
Average134.0907Da
Monoisotopic134.03275669Da
BASm0019931N-Acetylglutamic acidC7H11NO5Chemical structure of N-Acetylglutamic acid1188-37-0
Average189.1659Da
Monoisotopic189.063722467Da
BASm00200897-Methylguanosine 5'-phosphateC11H17N5O8PChemical structure of 7-Methylguanosine 5'-phosphate10162-58-0
Average378.2551Da
Monoisotopic378.081474057Da
BASm0020115(6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterinC9H14N4O3Chemical structure of (6R)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterinNULL
Average226.2325Da
Monoisotopic226.106590334Da
BASm0020478Geranyl acetoneC13H22OChemical structure of Geranyl acetone67-64-1
Average194.318Da
Monoisotopic194.167065328Da
BASm0034737(6S)-5,6,7,8-tetrahydrofolic acidC19H23N7O6Chemical structure of (6S)-5,6,7,8-tetrahydrofolic acidNULL
Average445.4292Da
Monoisotopic445.170981503Da
BASm00347382-oxobutanoic acidC4H5O3Chemical structure of 2-oxobutanoic acidNULL
Average101.0807Da
Monoisotopic101.023869026Da

Displaying 81–88 of 88 metabolites