Burkholderia mallei

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia mallei is a Gram-negative, rod-shaped bacterium that is primarily associated with host organisms. This microbe is an obligate aerobe, meaning it requires oxygen for its growth and metabolism. As a member of the Burkholderia genus, B. mallei is notably adapted to a host-associated environment, which may influence its interactions with both the host and the surrounding microbial community. The habitat of B. mallei is significant as it underscores the bacterium's specialized adaptations for survival and proliferation in a host. This adaptation may facilitate its ability to exploit host resources while also navigating the complex immune responses elicited by the host organism. The pathogenic potential of B. mallei, associated with glanders disease in equines, further highlights its ecological niche and the implications of host-associated lifestyles in microbial evolution. In terms of ecological insight, B. mallei's existence as a strictly aerobic organism suggests a competitive advantage in oxygen-rich environments, enabling it to outcompete other microorganisms that may inhabit similar niches. This adaptation may influence the dynamics of microbial communities within the host, potentially affecting host health and disease outcomes. Overall, the traits of Burkholderia mallei reflect its specialized role within host ecosystems and underline the intricate relationships between pathogens and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia mallei
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Burkholderia mallei
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Burkholderia mallei

Accession NumberRKJX00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

5832 genes

Non-Coding Genes

70 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
copper homeostasis protein cutcEGT66_00065Not Available+10018 - 1073124289.2
biotin synthase biobEGT66_00070Not Available-10858 - 1187737017.2
atp-dependent dethiobiotin synthetase biodEGT66_00075Not Available-11941 - 1266324875.2
8-amino-7-oxononanoate synthaseEGT66_00080Not Available-12660 - 1384440701.5
adenosylmethionine--8-amino-7-oxononanoate transaminaseEGT66_00085Not Available-13841 - 1518749317.6
hypothetical proteinEGT66_00090Not Available-15751 - 1703445372.1
hypothetical proteinEGT66_00095Not Available-17263 - 1771516425.2
sdr family oxidoreductaseEGT66_00100Not Available-17747 - 1843023616.6
acetyl-coa c-acyltransferaseEGT66_00105Not Available-18461 - 1965440917.5
carbonate dehydrataseEGT66_00110Not Available-19641 - 2041128231.6

Displaying genes 11 – 20 of 5902 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm0003692N-succinyl-L-glutamateC9H10NO7Chemical structure of N-succinyl-L-glutamateNot available
Average244.181Da
Monoisotopic244.047372406Da
BASm0003763(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateC11H12NO6PChemical structure of (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphateNot available
Average285.1898Da
Monoisotopic285.0402236Da
BASm0003896ADP-D-glycero-beta-D-manno-heptoseC17H25N5O16P2Chemical structure of ADP-D-glycero-beta-D-manno-heptoseNot available
Average617.355Da
Monoisotopic617.078250901Da
BASm0003934Co-precorrin-5BC43H42CoN4O16Chemical structure of Co-precorrin-5BNot available
Average929.759Da
Monoisotopic929.197164Da
BASm0003935Co-precorrin-6AC44H45CoN4O16Chemical structure of Co-precorrin-6ANot available
Average944.793Da
Monoisotopic944.22009Da
BASm0003971heme bC34H30FeN4O4Not available14875-96-8
Average614.484Da
Monoisotopic614.162739Da
BASm0003997Fe(II)-heme oC49H56FeN4O5Chemical structure of Fe(II)-heme oNot available
Average836.856Da
Monoisotopic836.361104Da
BASm0004092UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineC41H61N9O28P2Chemical structure of UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineNot available
Average1189.924Da
Monoisotopic1189.312320676Da
BASm0004093di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineC87H139N7O23P2Chemical structure of di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineNot available
Average1713.045Da
Monoisotopic1711.941952079Da
BASm0004094di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineC95H152N8O28P2Chemical structure of di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineNot available
Average1916.239Da
Monoisotopic1915.021324602Da

Displaying 41–50 of 88 metabolites