Streptomyces antibioticus

Gram-positive

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Kitasatosporales

Family

Streptomycetaceae

Genus

Streptomyces

Description

Streptomyces antibioticus is a Gram-positive bacterium notable for its ability to produce a variety of bioactive compounds, including the antibiotic streptomycin. This filamentous microbe belongs to the genus Streptomyces, which is well-known for its role in natural antibiotic production and soil ecology. Characteristically, S. antibioticus exhibits a complex life cycle that includes the formation of mycelium and spores, contributing to its resilience in various environments. The Gram-positive nature of S. antibioticus is indicative of its thick peptidoglycan layer, which is a common feature among members of this genus and plays a critical role in maintaining cell integrity. This structural characteristic is essential for its survival in competitive microbial communities, particularly in soil environments where it can engage in interactions with other microorganisms. S. antibioticus is primarily recognized for its production of streptomycin, an aminoglycoside antibiotic that has been instrumental in the treatment of bacterial infections, particularly those caused by Mycobacterium tuberculosis. The ability of this bacterium to synthesize such potent compounds highlights its ecological significance, as it may contribute to the regulation of microbial populations in its natural habitat. In summary, Streptomyces antibioticus exemplifies the intricate relationships between microbial physiology, antibiotic production, and ecological interactions, underscoring the importance of soil-dwelling actinomycetes in both health and disease management.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderKitasatosporales
FamilyStreptomycetaceae
GenusStreptomyces
SpeciesStreptomyces antibioticus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptomyces antibioticus

Accession NumberLGUX00000000.1

Gene Summary

Adenine Count

1401744 bp

Thymine Count

1401959 bp

Guanine Count

3567324 bp

Cytosine Count

3607817 bp

Genome Length

9978861 bp

Protein-coding Genes

8407 genes

Non-Coding Genes

85 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
ketol-acid reductoisomeraseADK77_00005Q9FBT8+1 - 80329246.8
Ncrna_class:otherNot AvailableNot Available+170 - 244Not Available
5s ribosomal rnaNot AvailableNot Available+210 - 326Not Available
16s ribosomal rnaNot AvailableNot Available+618 - 2149Not Available
Ncrna_class:otherNot AvailableNot Available+1006 - 1080Not Available
peroxidaseADK77_00010Q743F4-1102 - 209435897.3
hypothetical proteinADK77_00015Not Available-2133 - 295730716.2
Ncrna_class:otherNot AvailableNot Available+3475 - 3549Not Available
glyoxalaseADK77_00025Not Available-3911 - 436615968.9
Ncrna_class:otherNot AvailableNot Available+4912 - 4980Not Available

Displaying genes 1 – 10 of 677 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

51 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002002glyoxylateC2HO3Chemical structure of glyoxylateNot available
Average73.0275Da
Monoisotopic72.9925689Da
BASm0002282(2R)-2,3-dihydroxy-3-methylbutanoateC5H9O4Chemical structure of (2R)-2,3-dihydroxy-3-methylbutanoateNot available
Average133.1226Da
Monoisotopic133.0500838Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da
BASm0002307(2R,3R)-2,3-dihydroxy-3-methylpentanoateC6H11O4Chemical structure of (2R,3R)-2,3-dihydroxy-3-methylpentanoateNot available
Average147.1491Da
Monoisotopic147.06573384Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm00031102-dehydro-3-deoxy-D-galactonateC6H10O6Chemical structure of 2-dehydro-3-deoxy-D-galactonateNot available
Average178.14Da
Monoisotopic178.0477381Da
BASm00032075-methyl-5,6,7,8-tetrahydromethanopterinC31H44N6O16PChemical structure of 5-methyl-5,6,7,8-tetrahydromethanopterinNot available
Average787.694Da
Monoisotopic787.2567871Da

Displaying 11–20 of 51 metabolites