Mycobacterium avium

Gram-positiveRodNon-motileMicroaerophile

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium avium is a mesophilic microbe, preferring temperatures between 25-40°C, and is a heterotroph, deriving its energy from organic molecules. It employs aerobic respiration as its primary method of energy production, utilizing oxygen to break down its carbon-based energy sources. As a Gram-positive bacterium, M. avium's cell wall is composed of a thick peptidoglycan layer, which gives it a distinctive staining characteristic. Its shape is typically coccobacillary, with smooth, non-motile, and non-spore-forming cells. M. avium can be found in various body sites, including the respiratory tract, skin, and gastrointestinal tract, across all mammalian species. Its presence is often asymptomatic, but it can also cause opportunistic infections in individuals with compromised immune systems. The microbe is an obligate aerobe, requiring a constant supply of oxygen to survive. It thrives in environments with moderate to high levels of oxygen, such as the human lung and intestinal tract. One notable characteristic of M. avium is its ability to form biofilms, complex communities of microorganisms attached to surfaces. This allows it to adapt to its environment and resist host immune responses. In addition to its biological characteristics, M. avium has gained significant attention in recent years due to its potential role in the development of disease. The microbe's ability to form biofilms and evade host immune responses makes it a challenging target for treatment, and its presence has been implicated in various respiratory and gastrointestinal disorders. Furthermore, the increasing prevalence of antibiotic-resistant strains has led to increased research into the development of novel therapeutic strategies against M. avium.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium avium
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Mycobacterium avium
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Mycobacterium avium

Accession NumberNSEV00000000.1

Gene Summary

Adenine Count

827038 bp

Thymine Count

828601 bp

Guanine Count

1836406 bp

Cytosine Count

1843130 bp

Genome Length

5335175 bp

Protein-coding Genes

4816 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
succinate dehydrogenaseCKJ75_19650Not Available+4126361 - 412683118037.9
succinate dehydrogenase flavoprotein subunitCKJ75_19655Not Available+4126839 - 412859364362.8
succinate dehydrogenase iron-sulfur subunitCKJ75_19660Not Available+4128594 - 412939729872.0
carboxymuconolactone decarboxylase family proteinCKJ75_19665Not Available+4129584 - 413019822617.7
rna polymerase sigma factor sigjCKJ75_19670Not Available-4130173 - 413108132415.8
aspartate aminotransferase family proteinCKJ75_19675Not Available+4131128 - 413245948049.2
hypothetical proteinCKJ75_19680Not Available-4132434 - 41326859110.95
d-alanyl-d-alanine carboxypeptidaseCKJ75_19685Not Available+4132900 - 413415942783.9
mfs transporterCKJ75_19690Not Available+4134165 - 413551747701.4
n-acetylglucosamine-6-phosphate deacetylaseCKJ75_19695Not Available+4135508 - 413664439123.8

Displaying genes 3771 – 3780 of 4869 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites