Cutibacterium acnes str. 11-78

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes strain 11-78 is a Gram-positive, nonsporulating rod-shaped bacterium that thrives in anaerobic environments, with an optimal growth temperature of 37.0 °C. This microbe is primarily associated with host organisms, suggesting a specific relationship with its host environment, which is typical for many members of the Cutibacterium genus. C. acnes is known for its role in the human microbiome, particularly on the skin, where it can contribute to the maintenance of skin health as well as being implicated in various skin conditions. Its anaerobic nature indicates that it metabolizes substrates in the absence of oxygen, a trait that aligns with its ecological niche on human skin and within hair follicles. The ability to survive and proliferate at the human body temperature further underscores its adaptation to a host-associated lifestyle. The ecological role of C. acnes str. 11-78 may extend beyond mere commensalism, as it may play a crucial role in skin homeostasis by outcompeting pathogenic organisms and contributing to the skin's microbial diversity. Understanding the specific interactions and functions of this strain within the host microbiome could provide insights into its potential influence on skin health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes str. 11-78
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes str. 11-78

Accession NumberNZ_CM008362.1

Gene Summary

Adenine Count

10090 bp

Thymine Count

10211 bp

Guanine Count

16891 bp

Cytosine Count

16841 bp

Genome Length

54033 bp

Protein-coding Genes

73 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
phosphoribosylglycinamide formyltransferaseB1B09_10485Not Available-2086433 - 208705622263.9
6,7-dimethyl-8-ribityllumazine synthaseB1B09_10490Not Available-2087081 - 208758116783.9
bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase iiB1B09_10495Not Available-2087578 - 208889446656.4
riboflavin synthaseB1B09_10500Not Available-2088888 - 208950221551.9
riboflavin biosynthesis protein ribdB1B09_10505Not Available-2089495 - 209049035208.8
hypothetical proteinB1B09_10510Not Available-2090776 - 209226951912.4
succinate--coa ligase subunit alphaB1B09_10515Not Available-2092419 - 209331230567.9
succinate--coa ligase subunit betaB1B09_10520Not Available-2093316 - 209449141359.5
hypothetical proteinB1B09_10525Not Available+2094471 - 209476110894.2
dna helicase pcraB1B09_10530Not Available-2094718 - 209715089618.8

Displaying genes 2091 – 2100 of 2543 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites