Bifidobacterium breve str. CNCM I-4321

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. CNCM I-4321 is a Gram-positive, anaerobic bacterium predominantly found in the gastrointestinal tract, particularly within the gut microbiota of healthy newborns and infants, as well as in human breast milk. This strain is part of a diverse community of beneficial microbes that inhabit the intestines, playing a crucial role in gut health and development during early life. This species thrives in anaerobic conditions, which are characteristic of the gut environment, facilitating its growth and activity in the absence of oxygen. Its presence in human breast milk underscores its importance in shaping the infant gut microbiome, as it may contribute to the establishment of a healthy microbial community essential for proper digestion and immune system development. Bifidobacterium breve str. CNCM I-4321's adaptation to the infant intestine suggests a specialized role in metabolizing human milk oligosaccharides, which are abundant in breast milk. This unique ability not only aids in the digestion of these complex carbohydrates but may also enhance the overall health of the infant by promoting a balanced gut microbiota. Consequently, understanding the functional capabilities of this strain could provide insights into its potential applications in probiotic formulations targeted at improving infant health and development.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve str. CNCM I-4321

Accession NumberNZ_CP021559.1

Gene Summary

Adenine Count

507424 bp

Thymine Count

504369 bp

Guanine Count

723847 bp

Cytosine Count

729212 bp

Genome Length

2464852 bp

Protein-coding Genes

2082 genes

Non-Coding Genes

140 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
cell division proteinCNCMI4321_RS02245Not Available-482318 - 48310328364.0
pantetheine-phosphate adenylyltransferaseCNCMI4321_RS02250Not Available-483109 - 48360917770.4
duf3039 domain-containing proteinCNCMI4321_RS02255Not Available+483714 - 48399510320.1
aldo/keto reductaseCNCMI4321_RS02260Not Available-484191 - 48520137248.3
merr family transcriptional regulatorCNCMI4321_RS02265Not Available+485460 - 48588816802.8
pr6pr family membrane proteinCNCMI4321_RS02270Not Available-485896 - 48652223482.3
nicotinate phosphoribosyltransferaseCNCMI4321_RS02275Not Available+486630 - 48795247525.5
ribonuclease phCNCMI4321_RS02280Not Available+488502 - 48926627750.3
non-canonical purine ntp pyrophosphataseCNCMI4321_RS02285Not Available+489391 - 49016426609.4
aec family transporterCNCMI4321_RS02290Not Available-490290 - 49129135823.0

Displaying genes 511 – 520 of 2222 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–1 of 1 metabolites