Bifidobacterium breve str. CNCM I-4321

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. CNCM I-4321 is a Gram-positive, anaerobic bacterium predominantly found in the gastrointestinal tract, particularly within the gut microbiota of healthy newborns and infants, as well as in human breast milk. This strain is part of a diverse community of beneficial microbes that inhabit the intestines, playing a crucial role in gut health and development during early life. This species thrives in anaerobic conditions, which are characteristic of the gut environment, facilitating its growth and activity in the absence of oxygen. Its presence in human breast milk underscores its importance in shaping the infant gut microbiome, as it may contribute to the establishment of a healthy microbial community essential for proper digestion and immune system development. Bifidobacterium breve str. CNCM I-4321's adaptation to the infant intestine suggests a specialized role in metabolizing human milk oligosaccharides, which are abundant in breast milk. This unique ability not only aids in the digestion of these complex carbohydrates but may also enhance the overall health of the infant by promoting a balanced gut microbiota. Consequently, understanding the functional capabilities of this strain could provide insights into its potential applications in probiotic formulations targeted at improving infant health and development.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve str. CNCM I-4321

Accession NumberNZ_CP021559.1

Gene Summary

Adenine Count

507424 bp

Thymine Count

504369 bp

Guanine Count

723847 bp

Cytosine Count

729212 bp

Genome Length

2464852 bp

Protein-coding Genes

2082 genes

Non-Coding Genes

140 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Trna-leuNot AvailableNot Available+491560 - 491640Not Available
Trna-thrNot AvailableNot Available+491732 - 491807Not Available
glucose-6-phosphate isomeraseCNCMI4321_RS02305Not Available+492166 - 49386662900.8
nitrate/sulfonate/bicarbonate abc transporter atp-binding proteinCNCMI4321_RS02310Not Available-494346 - 49576451341.5
abc transporter permeaseCNCMI4321_RS02315Not Available-495892 - 49768265454.5
50s ribosomal protein l19CNCMI4321_RS02325Not Available+498473 - 49883813628.6
signal peptidase iCNCMI4321_RS02330Not Available+499007 - 49993033193.5
ribonuclease hiiCNCMI4321_RS02335Not Available+499958 - 50081530015.3
laci family dna-binding transcriptional regulatorCNCMI4321_RS02340Not Available+500977 - 50209240664.8
glycoside hydrolase family 3 n-terminal domain-containing proteinCNCMI4321_RS02345Not Available+502259 - 5023784131.08

Displaying genes 521 – 530 of 2222 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–1 of 1 metabolites