Bifidobacterium breve

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve is a Gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a Chemoheterotroph, and can be found in various body sites across all species, including the gut, respiratory, and urinary tracts, and is an Obligate Anaerobe. As a Gram-positive microbe, Bifidobacterium breve has a thick peptidoglycan layer in its cell wall, providing it with a strong defense against environmental stresses. Its rod-shaped morphology allows it to adapt to different environments and interact with various surfaces. The mesophilic temperature preference of Bifidobacterium breve enables it to grow and multiply in temperatures ranging from 20-45°C, making it suitable for human and animal hosts. As a Chemoheterotroph, Bifidobacterium breve relies on organic compounds for energy and carbon sources, breaking down complex molecules into simpler ones to sustain its growth. Its presence in various body sites suggests its ability to colonize and thrive in diverse environments. The Obligate Anaerobe nature of Bifidobacterium breve means it requires the absence of oxygen to survive, which is why it is typically found in areas with low oxygen levels, such as the gut. Bifidobacterium breve plays a crucial role in maintaining the balance of the microbiome and has been shown to have probiotic properties, aiding in digestion and immune system function. It has also been found to produce antimicrobial compounds that inhibit the growth of pathogenic bacteria, making it a valuable microbe in the prevention and treatment of various diseases.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve


Gene Summary

Adenine Count

473596 bp

Thymine Count

472816 bp

Guanine Count

671214 bp

Cytosine Count

671285 bp

Genome Length

2288919 bp

Protein-coding Genes

1770 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
cellodextrin transport system transcriptional regulatorB7017_0120O87590+156543 - 15754736682.1
cellodextrin binding proteinB7017_0121P94528+157728 - 15903547293.5
cellodextrin transport system permease protein cebfB7017_0122P29823+159114 - 16023541450.8
cellodextrin transport system permease protein cebgB7017_0123P29824+160243 - 16119033985.1
beta-glucosidase, cellodextrinase, glycosyl hydrolase family 1B7017_0124P94248+161297 - 16269752133.2
ketol-acid reductoisomerase/2-dehydropantoate 2-reductaseB7017_0125Q8G6V2+162962 - 16401438578.6
hypothetical proteinB7017_0126Not Available-164295 - 16508629841.6
membrane proteinB7017_0127Not Available-165083 - 16611138921.6
alpha-glucosidaseB7017_0128O16098-166318 - 16813267075.7
transcriptional regulator, laci familyB7017_0129Q8DAQ5-168404 - 16943536552.5

Displaying genes 2061 – 2070 of 3786 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites