Streptococcus oralis

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis is a microbe that thrives in a temperature range of 25-40°C, classified as a mesophile. This Gram-positive, rod-shaped bacterium is a heterotroph, meaning it derives its energy by breaking down organic compounds. Specifically, it employs anaerobic fermentation as its primary energy production method, utilizing glucose and other simple sugars as its energy source. Upon examination, S. oralis exhibits a typical coccus (spherical) morphology, with flat, smooth surfaces and a diameter of approximately 0.5-1.2 μm. It is widely distributed across various body sites, including the oral cavity, pharynx, and gastrointestinal tract, with a presence in all human species. In terms of its oxygen preference, S. oralis is an aerotolerant anaerobe, meaning it can grow in the presence of oxygen but does not require it for survival. This adaptability allows it to thrive in environments with varying oxygen levels. Streptococcus oralis is an opportunistic pathogen, often implicated in infections of the oral and respiratory tracts. It is also a key inhabitant of the human oral microbiome, playing a crucial role in maintaining oral health by regulating the colonization of other microorganisms. Notably, S. oralis has been linked to various oral diseases, including dental caries, periodontitis, and endocarditis. Its ability to adhere to tooth surfaces and produce enzymes that break down complex carbohydrates makes it a significant contributor to these conditions. Furthermore, its presence has been associated with conditions such as halitosis, or bad breath, and can serve as a biomarker for the early detection of oral cancer.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceNot Available
Number of membranesNot Available
Image of Streptococcus oralis
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis

Accession NumberRJNM00000000.1

Gene Summary

Adenine Count

608532 bp

Thymine Count

606537 bp

Guanine Count

419988 bp

Cytosine Count

425705 bp

Genome Length

2065507 bp

Protein-coding Genes

1931 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

19

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
integral membrane protein (rhomboid family)SORDD14_01139P43984-1167812 - 116833920274.8
sensor histidine kinase vncsSORDD14_01140Q47745-1168448 - 116978851649.3
dna-binding response regulatorSORDD14_01141Q47744-1169785 - 117043825135.6
hypothetical proteinSORDD14_01142Not Available+1170534 - 11706504358.33
atp-dependent clp protease atp-binding subunit clpaSORDD14_01143Q8EU05-1170695 - 117312790250.3
transcriptional regulator ctsrSORDD14_01144P37568-1173129 - 117358717623.2
hypothetical proteinSORDD14_01145Not Available+1173906 - 117500943430.5
hypothetical proteinSORDD14_01146Not Available-1175188 - 11753526438.87
hypothetical proteinSORDD14_01147Not Available-1175976 - 117652421602.7
hydroxymethylpyrimidine abc transporter, atpase componentSORDD14_01163Q9K9G7-1185883 - 118661127463.5

Displaying genes 1181 – 1190 of 34943 in total

Pathways

1 pathway

Metabolites

2 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014096Cyclic AMPC10H12N5O6PChemical structure of Cyclic AMPNULL
Average329.2059Da
Monoisotopic329.052519653Da
BASm0017263NADPC21H29N7O17P3Chemical structure of NADP53-59-8
Average744.4129Da
Monoisotopic744.083277073Da

Displaying 1–2 of 2 metabolites