Haemophilus parainfluenzae

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus parainfluenzae is a Gram-negative, coccobacillary-shaped microbe that thrives in mesophilic temperatures, classified as a Chemoheterotroph, and can be found in various body sites, including the respiratory, gastrointestinal, and genitourinary tracts, of humans and other species, and is a Facultative Anaerobe. The Gram-negative characteristic indicates that the microbe's cell wall is composed of a thin peptidoglycan layer, making it more susceptible to certain antibiotics. Its coccobacillary shape allows it to adhere to and colonize host cells, facilitating its ability to cause infections. As a mesophile, Haemophilus parainfluenzae grows optimally at temperatures between 20-45°C, which is consistent with the natural human body temperature.As a Chemoheterotroph, Haemophilus parainfluenzae requires organic compounds for energy and carbon sources, which it obtains from its host or environment. This characteristic is essential for its survival and pathogenicity. The microbe's ability to inhabit various body sites in different species highlights its adaptability and potential to cause a range of infections. Haemophilus parainfluenzae is often found in the human respiratory tract, where it can contribute to conditions such as pneumonia, bronchitis, and sinusitis. Its presence in other body sites, including the gastrointestinal and genitourinary tracts, can also lead to infections, particularly in individuals with compromised immune systems.Haemophilus parainfluenzae's classification as a Facultative Anaerobe means it can grow in the presence or absence of oxygen, allowing it to thrive in various environments. This flexibility is crucial for its survival and pathogenicity, as it can adapt to different oxygen levels in the host. The microbe's ability to survive in low-oxygen environments, such as the gastrointestinal tract, enables it to colonize and infect these areas. Haemophilus parainfluenzae has been implicated in several types of infections, including endocarditis, septicemia, and meningitis, particularly in individuals with underlying medical conditions or compromised immune systems. Its ability to form biofilms and adhere to host cells makes it a formidable pathogen, capable of causing severe and persistent infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus parainfluenzae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus parainfluenzae
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus parainfluenzae

Accession NumberQEPT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1880 genes

Non-Coding Genes

149 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Enoyl-coa hydratase/carnithine racemase-like proteinEL215_RS04300Not Available-854528 - 85501018672.2
Tail collarEL215_RS04305Not Available-855003 - 85562623254.4
Putative tail fiber proteinEL215_RS04310Not Available-855626 - 85724859199.5
Gp25, tail fiberEL215_RS04315Not Available-857275 - 85784121655.9
Baseplate j-like proteinEL215_RS04320Not Available-857834 - 85894040671.5
Baseplate wedge subunitEL215_RS04325Not Available-858937 - 85930214028.6
Baseplate assembly protein vEL215_RS04330Not Available-859362 - 85991019002.3
Tail proteinEL215_RS04335Not Available-859911 - 86098139580.4
Gp20, phage tail protein xEL215_RS04340Not Available-860974 - 8612078833.52
Gp45EL215_RS04345Not Available-861185 - 86214134651.4

Displaying genes 1 – 10 of 6428 in total

Pathways

23 pathways

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm0019198PS(18:0/18:1(9Z))C42H80NO10PChemical structure of PS(18:0/18:1(9Z))NULL
Average790.073Da
Monoisotopic789.551984778Da
BASm0019212PS(16:0/18:1(9Z))C40H76NO10PChemical structure of PS(16:0/18:1(9Z))NULL
Average762.019Da
Monoisotopic761.520684649Da
BASm0019214PS(16:1(9Z)/18:1(9Z))C40H74NO10PChemical structure of PS(16:1(9Z)/18:1(9Z))NULL
Average760.003Da
Monoisotopic759.505034585Da
BASm0020025myristoyl-CoAC35H62N7O17P3SChemical structure of myristoyl-CoA3130-72-1
Average977.89Da
Monoisotopic977.313573819Da
BASm0020027oleoyl-CoAC39H68N7O17P3SChemical structure of oleoyl-CoA1716-06-9
Average1031.98Da
Monoisotopic1031.360524011Da
BASm0020161PA(12:0/16:0)C31H61O8PChemical structure of PA(12:0/16:0)NULL
Average592.785Da
Monoisotopic592.41040544Da
BASm0020162PA(12:0/16:1(9Z))C31H59O8PChemical structure of PA(12:0/16:1(9Z))NULL
Average590.7691Da
Monoisotopic590.394755376Da
BASm0020164PA(14:1(9Z)/16:0)C33H63O8PChemical structure of PA(14:1(9Z)/16:0)NULL
Average618.8223Da
Monoisotopic618.426055504Da
BASm0020166PA(16:1(9Z)/18:1(9Z))C37H69O8PChemical structure of PA(16:1(9Z)/18:1(9Z))NULL
Average672.9127Da
Monoisotopic672.473005696Da
BASm0020169PA(18:0/18:1(9Z))C39H75O8PChemical structure of PA(18:0/18:1(9Z))384833-24-3
Average702.9818Da
Monoisotopic702.519955888Da

Displaying 61–70 of 88 metabolites