Haemophilus parainfluenzae

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus parainfluenzae is a Gram-negative, coccobacillary-shaped microbe that thrives in mesophilic temperatures, classified as a Chemoheterotroph, and can be found in various body sites, including the respiratory, gastrointestinal, and genitourinary tracts, of humans and other species, and is a Facultative Anaerobe. The Gram-negative characteristic indicates that the microbe's cell wall is composed of a thin peptidoglycan layer, making it more susceptible to certain antibiotics. Its coccobacillary shape allows it to adhere to and colonize host cells, facilitating its ability to cause infections. As a mesophile, Haemophilus parainfluenzae grows optimally at temperatures between 20-45°C, which is consistent with the natural human body temperature.As a Chemoheterotroph, Haemophilus parainfluenzae requires organic compounds for energy and carbon sources, which it obtains from its host or environment. This characteristic is essential for its survival and pathogenicity. The microbe's ability to inhabit various body sites in different species highlights its adaptability and potential to cause a range of infections. Haemophilus parainfluenzae is often found in the human respiratory tract, where it can contribute to conditions such as pneumonia, bronchitis, and sinusitis. Its presence in other body sites, including the gastrointestinal and genitourinary tracts, can also lead to infections, particularly in individuals with compromised immune systems.Haemophilus parainfluenzae's classification as a Facultative Anaerobe means it can grow in the presence or absence of oxygen, allowing it to thrive in various environments. This flexibility is crucial for its survival and pathogenicity, as it can adapt to different oxygen levels in the host. The microbe's ability to survive in low-oxygen environments, such as the gastrointestinal tract, enables it to colonize and infect these areas. Haemophilus parainfluenzae has been implicated in several types of infections, including endocarditis, septicemia, and meningitis, particularly in individuals with underlying medical conditions or compromised immune systems. Its ability to form biofilms and adhere to host cells makes it a formidable pathogen, capable of causing severe and persistent infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus parainfluenzae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus parainfluenzae
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus parainfluenzae

Accession NumberQEPT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1880 genes

Non-Coding Genes

149 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Hypothetical proteinEL215_RS10260Not Available-881480 - 8816506397.95
hypothetical proteinEL215_RS10265Not Available-881647 - 8818116146.31
Hypothetical proteinEL215_RS04500Not Available-881821 - 8820157683.0
Host-nuclease inhibitor proteinEL215_RS04505Not Available-882182 - 88270319531.2
hypothetical proteinEL215_RS04510Not Available-882696 - 8829449291.2
Hypothetical proteinEL215_RS04515Not Available-882955 - 88328112335.2
Phage transposaseEL215_RS04520Not Available-883281 - 88418733064.7
TransposaseEL215_RS04525Not Available-884211 - 88618175653.9
Dna binding protein nerEL215_RS04530Not Available-886190 - 8864028086.06
Transcriptional regulatory proteinEL215_RS04535Not Available+886605 - 88730326021.0

Displaying genes 41 – 50 of 6428 in total

Pathways

23 pathways

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm0018533CDP-DG(14:0/16:0)C42H77N3O15P2Chemical structure of CDP-DG(14:0/16:0)NULL
Average926.032Da
Monoisotopic925.482992787Da
BASm0018559CDP-DG(16:1(9Z)/18:1(9Z))C46H81N3O15P2Chemical structure of CDP-DG(16:1(9Z)/18:1(9Z))NULL
Average978.108Da
Monoisotopic977.514292916Da
BASm00188761-Acyl-sn-glycero-3-phosphoethanolamine (N-C12:0)C17H36NO7PNot availableNULL
Average397.449Da
Monoisotopic397.222939501Da
BASm00188771-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)C19H40NO7PChemical structure of 1-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)NULL
Average425.4972Da
Monoisotopic425.254239151Da
BASm00188791-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)C21H44NO7PChemical structure of 1-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)NULL
Average453.5503Da
Monoisotopic453.285539279Da
BASm00188811-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)C23H48NO7PChemical structure of 1-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)NULL
Average481.6035Da
Monoisotopic481.316839407Da
BASm00188831-Acyl-sn-glycero-3-phosphoglycerol (N-C12:0)C18H36O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C12:0)NULL
Average427.4468Da
Monoisotopic427.209694262Da
BASm00188841-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)C20H38O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)NULL
Average453.4841Da
Monoisotopic453.225344326Da
BASm00188851-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)C22H44O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)NULL
Average483.5531Da
Monoisotopic483.272294518Da
BASm00188861-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)C22H42O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)NULL
Average481.5372Da
Monoisotopic481.256644454Da

Displaying 31–40 of 88 metabolites