Haemophilus parainfluenzae

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus parainfluenzae is a Gram-negative, coccobacillary-shaped microbe that thrives in mesophilic temperatures, classified as a Chemoheterotroph, and can be found in various body sites, including the respiratory, gastrointestinal, and genitourinary tracts, of humans and other species, and is a Facultative Anaerobe. The Gram-negative characteristic indicates that the microbe's cell wall is composed of a thin peptidoglycan layer, making it more susceptible to certain antibiotics. Its coccobacillary shape allows it to adhere to and colonize host cells, facilitating its ability to cause infections. As a mesophile, Haemophilus parainfluenzae grows optimally at temperatures between 20-45°C, which is consistent with the natural human body temperature.As a Chemoheterotroph, Haemophilus parainfluenzae requires organic compounds for energy and carbon sources, which it obtains from its host or environment. This characteristic is essential for its survival and pathogenicity. The microbe's ability to inhabit various body sites in different species highlights its adaptability and potential to cause a range of infections. Haemophilus parainfluenzae is often found in the human respiratory tract, where it can contribute to conditions such as pneumonia, bronchitis, and sinusitis. Its presence in other body sites, including the gastrointestinal and genitourinary tracts, can also lead to infections, particularly in individuals with compromised immune systems.Haemophilus parainfluenzae's classification as a Facultative Anaerobe means it can grow in the presence or absence of oxygen, allowing it to thrive in various environments. This flexibility is crucial for its survival and pathogenicity, as it can adapt to different oxygen levels in the host. The microbe's ability to survive in low-oxygen environments, such as the gastrointestinal tract, enables it to colonize and infect these areas. Haemophilus parainfluenzae has been implicated in several types of infections, including endocarditis, septicemia, and meningitis, particularly in individuals with underlying medical conditions or compromised immune systems. Its ability to form biofilms and adhere to host cells makes it a formidable pathogen, capable of causing severe and persistent infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus parainfluenzae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus parainfluenzae
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Haemophilus parainfluenzae

Accession NumberQEPT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1880 genes

Non-Coding Genes

149 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Gp6EL215_RS04400Not Available-869396 - 87049940385.0
Virion morphogenesis proteinEL215_RS04405Not Available-870748 - 87121217600.3
Putative head morphogenesis proteinEL215_RS04410Not Available-871338 - 87259447949.1
Putative portal proteinEL215_RS04415Not Available-872596 - 87402353448.4
Terminase large subunitEL215_RS04420Not Available-874026 - 87525546134.9
Hypothetical proteinEL215_RS04425Not Available-875317 - 87588921057.4
Hypothetical proteinEL215_RS04430Not Available-875912 - 87620210830.2
Hypothetical proteinEL215_RS04435Not Available-876205 - 87653112382.1
hypothetical proteinEL215_RS04440Not Available-876528 - 8767559141.28
duf2681 domain-containing proteinEL215_RS04450Not Available-876943 - 8771949255.99

Displaying genes 21 – 30 of 6428 in total

Pathways

23 pathways

Metabolites

88 records
Metabolite IDMetabolite nameStructureCAS number
BASm0017691PS(14:0/18:1(11Z))C38H72NO10PChemical structure of PS(14:0/18:1(11Z))NULL
Average733.965Da
Monoisotopic733.48938452Da
BASm0017737PG(14:1(7Z)/14:1(7Z))C34H63O10PChemical structure of PG(14:1(7Z)/14:1(7Z))NULL
Average662.842Da
Monoisotopic662.415885227Da
BASm0017743Stearoyl-CoAC39H70N7O17P3SChemical structure of Stearoyl-CoA362-66-3
Average1033.996Da
Monoisotopic1033.376174075Da
BASm0017775PE(12:0/14:0)C31H62NO8PChemical structure of PE(12:0/14:0)NULL
Average607.81Da
Monoisotopic607.421304958Da
BASm0017777PE(12:0/16:0)C33H66NO8PChemical structure of PE(12:0/16:0)NULL
Average635.864Da
Monoisotopic635.452605087Da
BASm0017778PE(12:0/16:1(9Z))C33H64NO8PChemical structure of PE(12:0/16:1(9Z))NULL
Average633.848Da
Monoisotopic633.436955023Da
BASm0017781PE(12:0/18:1(11Z))C35H68NO8PChemical structure of PE(12:0/18:1(11Z))NULL
Average661.902Da
Monoisotopic661.468255152Da
BASm0018523CDP-DG(12:0/14:0)C38H69N3O15P2Chemical structure of CDP-DG(12:0/14:0)NULL
Average869.924Da
Monoisotopic869.42039253Da
BASm0018525CDP-DG(12:0/16:0)C40H73N3O15P2Chemical structure of CDP-DG(12:0/16:0)NULL
Average897.978Da
Monoisotopic897.451692659Da
BASm0018526CDP-DG(12:0/16:1(9Z))C40H71N3O15P2Chemical structure of CDP-DG(12:0/16:1(9Z))NULL
Average895.962Da
Monoisotopic895.436042594Da

Displaying 21–30 of 88 metabolites