Escherichia coli O157:H7

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli O157:H7 is a Gram-negative, rod-shaped bacterium that typically appears in pairs or as single cells. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. E. coli O157:H7 has an optimal temperature of approximately 37.0°C, which coincides with the average human body temperature, suggesting a significant association with warm-blooded hosts. The habitat of E. coli O157:H7 is primarily host-associated, indicating a strong relationship with the gastrointestinal tracts of animals, particularly ruminants such as cattle. This association highlights the bacterium's potential for transmission through the food chain, particularly in undercooked or contaminated food products. Furthermore, the facultative anaerobic nature of E. coli O157:H7 may confer advantages in fluctuating oxygen conditions within the gut environment, allowing it to maintain metabolic versatility. Unique to E. coli O157:H7 is its adaptation to thrive in host-associated niches, which not only facilitates its survival but may also influence its interactions with the host microbiome. This interplay could have implications for both microbial community dynamics and host health, underscoring the importance of understanding this pathogen's role in the broader ecological context of gut microbiota.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli O157:H7
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Escherichia coli O157:H7

Accession NumberNZ_CP017669.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4581 genes

Non-Coding Genes

1004 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
incfii family plasmid replication initiator repaCAM50_RS27370Not Available+1 - 85832717.6
copg family ribbon-helix-helix proteinCAM50_RS27385Not Available+1771 - 205510475.5
type ii toxin-antitoxin system rele/pare family toxinCAM50_RS27390Not Available+2055 - 233010736.0
hypothetical proteinCAM50_RS27395Not Available+2425 - 26318001.41
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27400Not Available-2731 - 29468215.67
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27405Not Available-2990 - 355621523.5
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27410Not Available-3556 - 397216036.6
hypothetical proteinCAM50_RS27415Not Available-3972 - 41576876.23
catalase/peroxidase katpCAM50_RS27420Not Available+4334 - 654481798.5
cytochrome b562CAM50_RS27425Not Available+6588 - 697714582.7

Displaying genes 1 – 10 of 11382 in total

Pathways

12367 pathways

Metabolites

790 records
Metabolite IDMetabolite nameStructureCAS number
BASm0003308N(2)-succinyl-L-arginineC10H17N4O5Chemical structure of N(2)-succinyl-L-arginineNot available
Average273.27Da
Monoisotopic273.120443243Da
BASm00034237-phospho-2-dehydro-3-deoxy-D-arabino-heptonateC7H10O10PChemical structure of 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonateNot available
Average285.122Da
Monoisotopic285.0028043Da
BASm00034334-amino-4-deoxychorismateC10H10NO5Chemical structure of 4-amino-4-deoxychorismate133442-18-9
Average224.193Da
Monoisotopic224.056446006Da
BASm0003462(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinateC13H19N4O12PChemical structure of (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate3031-95-6
Average454.2833Da
Monoisotopic454.0737086Da
BASm0003645UDP-4-amino-4-deoxy-beta-L-arabinoseC14H22N3O15P2Chemical structure of UDP-4-amino-4-deoxy-beta-L-arabinoseNot available
Average534.2831Da
Monoisotopic534.0526151Da
BASm0003656N-acetyl-beta-D-muramate 6-phosphateC11H17NO11PChemical structure of N-acetyl-beta-D-muramate 6-phosphateNot available
Average370.228Da
Monoisotopic370.0555681Da
BASm00036917,8-dihydroneopterin 3'-phosphateC9H12N5O7PChemical structure of 7,8-dihydroneopterin 3'-phosphateNot available
Average333.1946Da
Monoisotopic333.047434275Da
BASm0003692N-succinyl-L-glutamateC9H10NO7Chemical structure of N-succinyl-L-glutamateNot available
Average244.181Da
Monoisotopic244.047372406Da
BASm0003810propanoyl phosphateC3H5O5PChemical structure of propanoyl phosphate121-69-7
Average152.043Da
Monoisotopic151.9885574Da
BASm0003889(S)-2-ureidoglycineC3H7N3O3Chemical structure of (S)-2-ureidoglycineNot available
Average133.106Da
Monoisotopic133.048741105Da

Displaying 31–40 of 790 metabolites