Escherichia coli O157:H7

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli O157:H7 is a Gram-negative, rod-shaped bacterium that typically appears in pairs or as single cells. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. E. coli O157:H7 has an optimal temperature of approximately 37.0°C, which coincides with the average human body temperature, suggesting a significant association with warm-blooded hosts. The habitat of E. coli O157:H7 is primarily host-associated, indicating a strong relationship with the gastrointestinal tracts of animals, particularly ruminants such as cattle. This association highlights the bacterium's potential for transmission through the food chain, particularly in undercooked or contaminated food products. Furthermore, the facultative anaerobic nature of E. coli O157:H7 may confer advantages in fluctuating oxygen conditions within the gut environment, allowing it to maintain metabolic versatility. Unique to E. coli O157:H7 is its adaptation to thrive in host-associated niches, which not only facilitates its survival but may also influence its interactions with the host microbiome. This interplay could have implications for both microbial community dynamics and host health, underscoring the importance of understanding this pathogen's role in the broader ecological context of gut microbiota.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli O157:H7
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Escherichia coli O157:H7

Accession NumberNZ_CP017669.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4581 genes

Non-Coding Genes

1004 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
incfii family plasmid replication initiator repaCAM50_RS27370Not Available+1 - 85832717.6
copg family ribbon-helix-helix proteinCAM50_RS27385Not Available+1771 - 205510475.5
type ii toxin-antitoxin system rele/pare family toxinCAM50_RS27390Not Available+2055 - 233010736.0
hypothetical proteinCAM50_RS27395Not Available+2425 - 26318001.41
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27400Not Available-2731 - 29468215.67
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27405Not Available-2990 - 355621523.5
conjugative transfer relaxase/helicase trai domain-containing proteinCAM50_RS27410Not Available-3556 - 397216036.6
hypothetical proteinCAM50_RS27415Not Available-3972 - 41576876.23
catalase/peroxidase katpCAM50_RS27420Not Available+4334 - 654481798.5
cytochrome b562CAM50_RS27425Not Available+6588 - 697714582.7

Displaying genes 1 – 10 of 11382 in total

Pathways

12367 pathways

Metabolites

790 records
Metabolite IDMetabolite nameStructureCAS number
BASm0002643itaconyl-CoAC26H40N7O19P3SChemical structure of itaconyl-CoA6008-93-1
Average879.618Da
Monoisotopic879.1312524Da
BASm0002644(9Z,12Z)-octadecadienoyl-CoAC39H62N7O17P3SChemical structure of (9Z,12Z)-octadecadienoyl-CoA6709-57-5
Average1025.94Da
Monoisotopic1025.31577Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0002759dTDP-beta-L-rhamnoseC16H24N2O15P2Not availableNot available
Average546.316Da
Monoisotopic546.066289237Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm00030862-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphateC34H64NO12PChemical structure of 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphateNot available
Average709.8452Da
Monoisotopic709.416613029Da
BASm00031962-dehydro-3-deoxy-D-glucarateC6H6O7Chemical structure of 2-dehydro-3-deoxy-D-glucarateNot available
Average190.108Da
Monoisotopic190.0124497Da
BASm00032855-methyltetrahydropteroyltri-L-glutamateC30H35N9O12Chemical structure of 5-methyltetrahydropteroyltri-L-glutamateNot available
Average713.663Da
Monoisotopic713.2427119Da
BASm0003296L-ribulose 5-phosphateC5H9O8PChemical structure of L-ribulose 5-phosphateNot available
Average228.094Da
Monoisotopic228.0046014Da

Displaying 21–30 of 790 metabolites