Neisseria lactamica

Gram-negativeCocciNon-motile

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria lactamica is a Gram-negative, diplococci-shaped bacterium that thrives at human body temperature (37°C), categorizing it as a mesophilic microbe. It is a chemoheterotroph, deriving its carbon and energy from organic compounds, and is predominantly found in the nasopharynx of humans but can also inhabit other mucosal surfaces, including the throat and respiratory tract. This organism acts as a facultative anaerobe, which means it can grow in both aerobic and anaerobic environments, thus enhancing its resilience in various body sites with differing oxygen levels. As a member of the Neisseriaceae family, N. lactamica is closely related to Neisseria meningitidis and Neisseria gonorrhoeae, but it is typically non-pathogenic and is considered part of the normal flora. Its presence in the nasopharynx can even provide a competitive advantage against more virulent strains, possibly due to its ability to occupy ecological niches that would otherwise be available to pathogenic bacteria. The capacity of N. lactamica to undergo genetic transformation and horizontal gene transfer presents a fascinating aspect of its biology. It can acquire genetic material from its environment, which may include antibiotic resistance genes, thus serving as a potential reservoir for such traits in other Neisseria species. This bacterium plays a vital role in understanding the dynamics of microbial ecosystems within the human body and may contribute to elucidating the mechanisms of bacterial persistence and pathogenicity in related species. Additionally, studies have suggested that N. lactamica may influence the immune system, possibly impacting responses to other pathogens.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria lactamica
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Neisseria lactamica
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature35
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Neisseria lactamica

Accession NumberUGRO00000000.1

Gene Summary

Adenine Count

522462 bp

Thymine Count

519814 bp

Guanine Count

571263 bp

Cytosine Count

572353 bp

Genome Length

2185892 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
protein folaNCTC10616_01474Not Available-1615991 - 161647917741.4
opcaNCTC10616_01476Not Available+1617986 - 16182138155.77
uncharacterised proteinNCTC10616_01477Not Available+1618234 - 161859313150.7
come1NCTC10616_01478Not Available-1618801 - 161910010294.7
Trna-alaNot AvailableNot Available+1622764 - 1622839Not Available
Trna-ileNot AvailableNot Available+1622845 - 1622921Not Available
surface exposed proteinNCTC10616_01484Not Available+1625142 - 162660549438.0
phosphopantetheine adenylyltransferaseNCTC10616_01485Not Available-1626740 - 162725219373.3
integral membrane proteinNCTC10616_01486Not Available-1627481 - 162815223951.7
fe(2+)-trafficking proteinNCTC10616_01487Not Available-1628309 - 162857510238.2

Displaying genes 1471 – 1480 of 2037 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

3 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0009321beta-D-fructose 1-phosphateC6H11O9PChemical structure of beta-D-fructose 1-phosphateNot available
Average258.12Da
Monoisotopic258.015166092Da

Displaying 1–3 of 3 metabolites