Moraxella catarrhalis

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Moraxellales

Family

Moraxellaceae

Genus

Moraxella

Description

Moraxella catarrhalis is a gram-negative, rod-shaped bacterium that thrives in temperatures ranging from 25-40°C, classified as psychrotolerant. As a heterotroph, it derives its energy from the breakdown of organic compounds, specifically utilizing aerobic respiration as its primary means of energy production. This process involves the conversion of glucose into ATP through the citric acid cycle and oxidative phosphorylation. M. catarrhalis is characterized by its Gram-staining properties, which indicate that it has a thin peptidoglycan layer. Its rod-shaped morphology allows it to thrive in a variety of environments, including the human respiratory tract, where it can be found colonizing the nasal cavity and sinuses. In addition, it has been detected in other body sites such as the throat, ear, and skin. As an obligate aerobe, M. catarrhalis requires the presence of oxygen to survive and grow. This is reflected in its ability to thrive in the oxygen-rich environment of the human respiratory tract, where it can be found coexisting with other microorganisms. Its ability to adapt to different oxygen levels allows it to colonize diverse niches, making it a successful pathogen. Despite its ability to thrive in a variety of environments, M. catarrhalis is often associated with respiratory tract infections, particularly in individuals with compromised immune systems. Its ability to adhere to epithelial cells and produce exotoxins contributes to its pathogenic potential. Furthermore, its ability to resist the host's immune response through the production of outer membrane vesicles and adhesins enables it to evade detection and persist in the host. In conclusion, Moraxella catarrhalis is a unique microbe that has evolved to thrive in the human respiratory tract, exploiting its ability to adapt to different temperatures, oxygen levels, and metabolic conditions. Its ability to adhere to epithelial cells, produce exotoxins, and resist the host's immune response make it a successful pathogen. While it is often associated with respiratory tract infections, its ability to colonize diverse niches and resist immune detection make it a formidable opponent.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderMoraxellales
FamilyMoraxellaceae
GenusMoraxella
SpeciesMoraxella catarrhalis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Moraxella catarrhalis
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Moraxella catarrhalis

Accession NumberLXHT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1913 genes

Non-Coding Genes

151 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Hypothetical proteinAO365_0712Not Available+711770 - 71215314507.4
hypothetical proteinAO365_0713Not Available+712153 - 7123417673.29
Putative major tail proteinAO365_0714Not Available+712345 - 71325331929.9
hypothetical proteinAO365_0715Not Available+713337 - 7134835752.43
AttlNot AvailableNot Available+713379 - 713390Not Available
hypothetical proteinAO365_0716Not Available+713527 - 71398817103.4
hypothetical proteinAO365_0717Not Available+714024 - 7142639238.18
Phage tail tape measureAO365_0718Not Available+714290 - 718120137487.0
hypothetical proteinAO365_0719Not Available+718192 - 71859015055.7
Hypothetical proteinAO365_0720Not Available-718607 - 71901115020.9

Displaying genes 1 – 10 of 9220 in total

Pathways

23 pathways

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014058Myristic acidC14H28O2Chemical structure of Myristic acid544-63-8
Average228.3709Da
Monoisotopic228.20893014Da
BASm0014182Vaccenic acidC18H34O2Chemical structure of Vaccenic acidNULL
Average282.468Da
Monoisotopic282.255880335Da
BASm0014219Palmitoleic acidC16H30O2Chemical structure of Palmitoleic acidNULL
Average254.4082Da
Monoisotopic254.224580204Da
BASm0014222DiethanolamineC4H11NO2Chemical structure of DiethanolamineNULL
Average105.1356Da
Monoisotopic105.078978601Da
BASm0017263NADPC21H29N7O17P3Chemical structure of NADP53-59-8
Average744.4129Da
Monoisotopic744.083277073Da
BASm0017265Uridine diphosphate-N-acetylglucosamineC17H27N3O17P2Chemical structure of Uridine diphosphate-N-acetylglucosamine528-04-1
Average607.3537Da
Monoisotopic607.081569477Da
BASm0017395CDP-DG(16:0/18:1(9Z))C46H83N3O15P2Chemical structure of CDP-DG(16:0/18:1(9Z))NULL
Average980.124Da
Monoisotopic979.529942981Da
BASm0017399CDP-DG(18:0/18:1(9Z))C48H87N3O15P2Chemical structure of CDP-DG(18:0/18:1(9Z))NULL
Average1008.178Da
Monoisotopic1007.561243109Da
BASm0017409PA(16:0/18:1(9Z))C37H71O8PChemical structure of PA(16:0/18:1(9Z))NULL
Average674.941Da
Monoisotopic674.488656244Da
BASm0017415PA(18:1(9Z)/18:1(9Z))C39H73O8PChemical structure of PA(18:1(9Z)/18:1(9Z))14268-17-8
Average700.979Da
Monoisotopic700.504306309Da

Displaying 11–20 of 92 metabolites