Moraxella catarrhalis

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Moraxellales

Family

Moraxellaceae

Genus

Moraxella

Description

Moraxella catarrhalis is a gram-negative, rod-shaped bacterium that thrives in temperatures ranging from 25-40°C, classified as psychrotolerant. As a heterotroph, it derives its energy from the breakdown of organic compounds, specifically utilizing aerobic respiration as its primary means of energy production. This process involves the conversion of glucose into ATP through the citric acid cycle and oxidative phosphorylation. M. catarrhalis is characterized by its Gram-staining properties, which indicate that it has a thin peptidoglycan layer. Its rod-shaped morphology allows it to thrive in a variety of environments, including the human respiratory tract, where it can be found colonizing the nasal cavity and sinuses. In addition, it has been detected in other body sites such as the throat, ear, and skin. As an obligate aerobe, M. catarrhalis requires the presence of oxygen to survive and grow. This is reflected in its ability to thrive in the oxygen-rich environment of the human respiratory tract, where it can be found coexisting with other microorganisms. Its ability to adapt to different oxygen levels allows it to colonize diverse niches, making it a successful pathogen. Despite its ability to thrive in a variety of environments, M. catarrhalis is often associated with respiratory tract infections, particularly in individuals with compromised immune systems. Its ability to adhere to epithelial cells and produce exotoxins contributes to its pathogenic potential. Furthermore, its ability to resist the host's immune response through the production of outer membrane vesicles and adhesins enables it to evade detection and persist in the host. In conclusion, Moraxella catarrhalis is a unique microbe that has evolved to thrive in the human respiratory tract, exploiting its ability to adapt to different temperatures, oxygen levels, and metabolic conditions. Its ability to adhere to epithelial cells, produce exotoxins, and resist the host's immune response make it a successful pathogen. While it is often associated with respiratory tract infections, its ability to colonize diverse niches and resist immune detection make it a formidable opponent.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderMoraxellales
FamilyMoraxellaceae
GenusMoraxella
SpeciesMoraxella catarrhalis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Moraxella catarrhalis
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Moraxella catarrhalis

Accession NumberLXHT00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1913 genes

Non-Coding Genes

151 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
lema family proteinAO365_0966Not Available-946052 - 94667523059.3
sodium/alanine symporterAO365_0967O32060+947097 - 94860253680.1
aldehyde dehydrogenaseAO365_0968Q9FDS1-948829 - 95034055443.3
hypothetical proteinAO365_0969Not Available+950429 - 9506056521.12
cytochrome c-type biogenesis protein dsbd, protein-disulfide reductaseAO365_0970Q9HUW5-950621 - 95261271581.8
hypothetical proteinAO365_0971Not Available-952771 - 9528994915.77
cytochrome d ubiquinol oxidase subunit iiAO365_0972P0ABK4-952980 - 95412842494.5
cytochrome d ubiquinol oxidase subunit iAO365_0973Q09049-954131 - 95573559538.3
hypothetical proteinAO365_0974Not Available-955975 - 9561034564.88
sodium-dependent transporterAO365_0975P44849-956119 - 95760653184.6

Displaying genes 971 – 980 of 9220 in total

Pathways

23 pathways

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002002glyoxylateC2HO3Chemical structure of glyoxylateNot available
Average73.0275Da
Monoisotopic72.9925689Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm0004229CoA-disulfideC42H62N14O32P6S2Chemical structure of CoA-disulfideNot available
Average1524.99Da
Monoisotopic1524.156559Da
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm00063042-iminoacetateC2H3NO2Chemical structure of 2-iminoacetateNot available
Average73.0507Da
Monoisotopic73.01637835Da
BASm0012554N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanineC37H57N7O20Not availableNot available
Average919.893Da
Monoisotopic919.366934423Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da

Displaying 1–10 of 92 metabolites