Helicobacter pylori str. ZH88

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH88 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0 degrees Celsius, which aligns with its habitat as a host-associated microbe, typically found in the gastric mucosa of the stomach. As a member of the Helicobacter genus, H. pylori is known for its distinctive spiral morphology, which may facilitate its motility through viscous environments, such as gastric mucus. The microaerophilic nature of this strain indicates that it requires reduced levels of oxygen for growth, a condition prevalent in the gastric environment, where oxygen concentration is lower than in the atmosphere. Understanding the specific growth requirements and morphological traits of H. pylori strain ZH88 is crucial for elucidating its interactions with host systems and potential implications for human health. Given its adaptation to life in the stomach, this strain may provide insights into the mechanisms by which gastric-associated bacteria navigate extreme environments and maintain their viability in the presence of gastric acid and other defensive host factors.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. ZH88

Accession NumberRJHD00000000.1

Gene Summary

Adenine Count

505660 bp

Thymine Count

502613 bp

Guanine Count

319675 bp

Cytosine Count

320845 bp

Genome Length

1651403 bp

Protein-coding Genes

1474 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
tumor necrosis factor alpha-inducing proteinEC538_03495Not Available-713178 - 71375621877.7
disulfide bond formation protein bEC538_03505Not Available-714231 - 71570355562.3
hypothetical proteinEC538_03510Not Available-715713 - 7158776067.77
had family hydrolaseEC538_03515Not Available-716020 - 71779869233.2
2-oxoglutarate:acceptor oxidoreductaseEC538_03520Not Available-717911 - 71846520046.5
2-oxoglutarate ferredoxin oxidoreductase subunit betaEC538_03525Not Available-718465 - 71928630416.3
2-oxoglutarate synthase subunit alphaEC538_03530Not Available-719288 - 72041541536.4
4fe-4s dicluster domain-containing proteinEC538_03535Not Available-720415 - 72075612419.2
endolytic transglycosylase mltgEC538_03540Not Available-720942 - 72193137629.1
duf3971 domain-containing proteinEC538_03545Not Available+721849 - 724782110862.0

Displaying genes 651 – 660 of 1516 in total

Pathways

26 pathways

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites