Helicobacter pylori str. ZH88

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain ZH88 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0 degrees Celsius, which aligns with its habitat as a host-associated microbe, typically found in the gastric mucosa of the stomach. As a member of the Helicobacter genus, H. pylori is known for its distinctive spiral morphology, which may facilitate its motility through viscous environments, such as gastric mucus. The microaerophilic nature of this strain indicates that it requires reduced levels of oxygen for growth, a condition prevalent in the gastric environment, where oxygen concentration is lower than in the atmosphere. Understanding the specific growth requirements and morphological traits of H. pylori strain ZH88 is crucial for elucidating its interactions with host systems and potential implications for human health. Given its adaptation to life in the stomach, this strain may provide insights into the mechanisms by which gastric-associated bacteria navigate extreme environments and maintain their viability in the presence of gastric acid and other defensive host factors.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori str. ZH88

Accession NumberRJHD00000000.1

Gene Summary

Adenine Count

505660 bp

Thymine Count

502613 bp

Guanine Count

319675 bp

Cytosine Count

320845 bp

Genome Length

1651403 bp

Protein-coding Genes

1474 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
efflux rnd transporter permease subunitEC538_03440Not Available-697454 - 700540113720.0
efflux rnd transporter periplasmic adaptor subunitEC538_03445Not Available-700553 - 70125725982.3
tolc family proteinEC538_03450Not Available-701267 - 70270054662.0
uroporphyrinogen decarboxylaseEC538_03455Not Available-702709 - 70373138655.3
hypothetical proteinEC538_03460Not Available-703798 - 70436721247.1
3-methyladenine dna glycosylaseEC538_03465Not Available-704412 - 70506825264.6
flagellin aEC538_03470Not Available-705186 - 70671853287.6
hemolysinEC538_03480Not Available+708747 - 71004848335.0
pyridoxal phosphate-dependent aminotransferase family proteinEC538_03485Not Available+710071 - 71119242087.0
penicillin-binding proteinEC538_03490Not Available+711193 - 71317574339.7

Displaying genes 641 – 650 of 1516 in total

Pathways

26 pathways

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites